Glial overexpression of NGF enhances neuropathic pain and adrenergic sprouting into DRG following chronic sciatic constriction in mice

Adrenergic sprouts within axotomized dorsal root ganglia (DRG) may contribute to neuropathic pain, and may arise under the influence of nerve growth factor (NGF). We investigated effects of chronic constriction injury (CCI) on behavior and sprouting in mice in which NGF overexpression is driven by a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1998-07, Vol.251 (1), p.53-56
Hauptverfasser:	Ramer, Matt S, Kawaja, Michael D, Henderson, Jeff T, Roder, John C, Bisby, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Allodynia Animals Axons - physiology Axotomy Biological and medical sciences Chronic constriction injury Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction Dorsal root ganglia Ganglia, Spinal - physiology Ganglia, Spinal - physiopathology Gene Expression Regulation Glial Fibrillary Acidic Protein - genetics Glial protein Hot Temperature Male Medical sciences Mice Mice, Inbred C57BL Mice, Transgenic Nerve growth factor Nerve Growth Factors - genetics Nerve Growth Factors - physiology Nervous system (semeiology, syndromes) Neuroglia - physiology Neurology Neuropathic pain Pain - physiopathology Physical Stimulation Promoter Regions, Genetic Sciatic Nerve - physiology Sciatic Nerve - physiopathology Sympathetic Nervous System - physiopathology Sympathetic sprouting
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!