On the mechanisms of fatty acid transformations in membranes

Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Lipids 1981-11, Vol.16 (11), p.790-795
Hauptverfasser: Gan‐Elepano, Minerva, Aeberhard, Ernesto, Mead, James F.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 795
container_issue 11
container_start_page 790
container_title Lipids
container_volume 16
creator Gan‐Elepano, Minerva
Aeberhard, Ernesto
Mead, James F.
description Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.
doi_str_mv 10.1007/BF02535030
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73801779</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>15342326</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3540-c4519c0a69f9bc4c0c61817fd1d552fbdaae6bfe7f114cda760c5e7a497b41ad3</originalsourceid><addsrcrecordid>eNqFkM1LAzEQxYMotVYv3oWcPAirM5tk04AXrVYLhXrQc8hmE7qyH3WzRfrfG-miN4WBYeb9eDweIecI1wggb-7nkAomgMEBGaMQ00QxkIdkDJDyhKeAx-QkhPd4IldiREaZVHHkmNyuGtqvHa2dXZumDHWgrafe9P2OGlsWtO9ME3zb1aYv2ybQsolsncevC6fkyJsquLNhT8jb_PF19pwsV0-L2d0ysUxwSCwXqCyYTHmVW27BZjhF6QsshEh9Xhjjstw76RG5LYzMwAonDVcy52gKNiGXe99N135sXeh1XQbrqiqGaLdBSzYFlFL9C6JgPGVpFsGrPWi7NoTOeb3pytp0O42gvzvVv51G-GJw3ea1K37QocSow17_LCu3-8NJLxcvDyAVsC_QKn7y</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15342326</pqid></control><display><type>article</type><title>On the mechanisms of fatty acid transformations in membranes</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Gan‐Elepano, Minerva ; Aeberhard, Ernesto ; Mead, James F.</creator><creatorcontrib>Gan‐Elepano, Minerva ; Aeberhard, Ernesto ; Mead, James F.</creatorcontrib><description>Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.</description><identifier>ISSN: 0024-4201</identifier><identifier>EISSN: 1558-9307</identifier><identifier>DOI: 10.1007/BF02535030</identifier><identifier>PMID: 6796797</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer‐Verlag</publisher><subject>Albumins - pharmacology ; Animals ; Arachidonic Acid ; Arachidonic Acids - metabolism ; Brain - metabolism ; fatty acids ; Fatty Acids - metabolism ; Malonyl Coenzyme A - metabolism ; Membrane Lipids - metabolism ; Microsomes - metabolism ; Rats ; transformation</subject><ispartof>Lipids, 1981-11, Vol.16 (11), p.790-795</ispartof><rights>1981 American Oil Chemists' Society (AOCS)</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3540-c4519c0a69f9bc4c0c61817fd1d552fbdaae6bfe7f114cda760c5e7a497b41ad3</citedby><cites>FETCH-LOGICAL-c3540-c4519c0a69f9bc4c0c61817fd1d552fbdaae6bfe7f114cda760c5e7a497b41ad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6796797$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gan‐Elepano, Minerva</creatorcontrib><creatorcontrib>Aeberhard, Ernesto</creatorcontrib><creatorcontrib>Mead, James F.</creatorcontrib><title>On the mechanisms of fatty acid transformations in membranes</title><title>Lipids</title><addtitle>Lipids</addtitle><description>Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.</description><subject>Albumins - pharmacology</subject><subject>Animals</subject><subject>Arachidonic Acid</subject><subject>Arachidonic Acids - metabolism</subject><subject>Brain - metabolism</subject><subject>fatty acids</subject><subject>Fatty Acids - metabolism</subject><subject>Malonyl Coenzyme A - metabolism</subject><subject>Membrane Lipids - metabolism</subject><subject>Microsomes - metabolism</subject><subject>Rats</subject><subject>transformation</subject><issn>0024-4201</issn><issn>1558-9307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1LAzEQxYMotVYv3oWcPAirM5tk04AXrVYLhXrQc8hmE7qyH3WzRfrfG-miN4WBYeb9eDweIecI1wggb-7nkAomgMEBGaMQ00QxkIdkDJDyhKeAx-QkhPd4IldiREaZVHHkmNyuGtqvHa2dXZumDHWgrafe9P2OGlsWtO9ME3zb1aYv2ybQsolsncevC6fkyJsquLNhT8jb_PF19pwsV0-L2d0ysUxwSCwXqCyYTHmVW27BZjhF6QsshEh9Xhjjstw76RG5LYzMwAonDVcy52gKNiGXe99N135sXeh1XQbrqiqGaLdBSzYFlFL9C6JgPGVpFsGrPWi7NoTOeb3pytp0O42gvzvVv51G-GJw3ea1K37QocSow17_LCu3-8NJLxcvDyAVsC_QKn7y</recordid><startdate>198111</startdate><enddate>198111</enddate><creator>Gan‐Elepano, Minerva</creator><creator>Aeberhard, Ernesto</creator><creator>Mead, James F.</creator><general>Springer‐Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>198111</creationdate><title>On the mechanisms of fatty acid transformations in membranes</title><author>Gan‐Elepano, Minerva ; Aeberhard, Ernesto ; Mead, James F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3540-c4519c0a69f9bc4c0c61817fd1d552fbdaae6bfe7f114cda760c5e7a497b41ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Albumins - pharmacology</topic><topic>Animals</topic><topic>Arachidonic Acid</topic><topic>Arachidonic Acids - metabolism</topic><topic>Brain - metabolism</topic><topic>fatty acids</topic><topic>Fatty Acids - metabolism</topic><topic>Malonyl Coenzyme A - metabolism</topic><topic>Membrane Lipids - metabolism</topic><topic>Microsomes - metabolism</topic><topic>Rats</topic><topic>transformation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gan‐Elepano, Minerva</creatorcontrib><creatorcontrib>Aeberhard, Ernesto</creatorcontrib><creatorcontrib>Mead, James F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gan‐Elepano, Minerva</au><au>Aeberhard, Ernesto</au><au>Mead, James F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>On the mechanisms of fatty acid transformations in membranes</atitle><jtitle>Lipids</jtitle><addtitle>Lipids</addtitle><date>1981-11</date><risdate>1981</risdate><volume>16</volume><issue>11</issue><spage>790</spage><epage>795</epage><pages>790-795</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer‐Verlag</pub><pmid>6796797</pmid><doi>10.1007/BF02535030</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0024-4201
ispartof Lipids, 1981-11, Vol.16 (11), p.790-795
issn 0024-4201
1558-9307
language eng
recordid cdi_proquest_miscellaneous_73801779
source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Albumins - pharmacology
Animals
Arachidonic Acid
Arachidonic Acids - metabolism
Brain - metabolism
fatty acids
Fatty Acids - metabolism
Malonyl Coenzyme A - metabolism
Membrane Lipids - metabolism
Microsomes - metabolism
Rats
transformation
title On the mechanisms of fatty acid transformations in membranes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T18%3A39%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=On%20the%20mechanisms%20of%20fatty%20acid%20transformations%20in%20membranes&rft.jtitle=Lipids&rft.au=Gan%E2%80%90Elepano,%20Minerva&rft.date=1981-11&rft.volume=16&rft.issue=11&rft.spage=790&rft.epage=795&rft.pages=790-795&rft.issn=0024-4201&rft.eissn=1558-9307&rft_id=info:doi/10.1007/BF02535030&rft_dat=%3Cproquest_cross%3E15342326%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15342326&rft_id=info:pmid/6796797&rfr_iscdi=true