On the mechanisms of fatty acid transformations in membranes
Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support...
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Veröffentlicht in: | Lipids 1981-11, Vol.16 (11), p.790-795 |
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creator | Gan‐Elepano, Minerva Aeberhard, Ernesto Mead, James F. |
description | Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process. |
doi_str_mv | 10.1007/BF02535030 |
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The results of these and other studies support the idea that such reactions of membrane lipid fatty acids with membrane‐bound enzymes normally occur entirely within the membrane without release of free fatty acids to equilibrate with the fatty acid pool during the process.</description><subject>Albumins - pharmacology</subject><subject>Animals</subject><subject>Arachidonic Acid</subject><subject>Arachidonic Acids - metabolism</subject><subject>Brain - metabolism</subject><subject>fatty acids</subject><subject>Fatty Acids - metabolism</subject><subject>Malonyl Coenzyme A - metabolism</subject><subject>Membrane Lipids - metabolism</subject><subject>Microsomes - metabolism</subject><subject>Rats</subject><subject>transformation</subject><issn>0024-4201</issn><issn>1558-9307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1LAzEQxYMotVYv3oWcPAirM5tk04AXrVYLhXrQc8hmE7qyH3WzRfrfG-miN4WBYeb9eDweIecI1wggb-7nkAomgMEBGaMQ00QxkIdkDJDyhKeAx-QkhPd4IldiREaZVHHkmNyuGtqvHa2dXZumDHWgrafe9P2OGlsWtO9ME3zb1aYv2ybQsolsncevC6fkyJsquLNhT8jb_PF19pwsV0-L2d0ysUxwSCwXqCyYTHmVW27BZjhF6QsshEh9Xhjjstw76RG5LYzMwAonDVcy52gKNiGXe99N135sXeh1XQbrqiqGaLdBSzYFlFL9C6JgPGVpFsGrPWi7NoTOeb3pytp0O42gvzvVv51G-GJw3ea1K37QocSow17_LCu3-8NJLxcvDyAVsC_QKn7y</recordid><startdate>198111</startdate><enddate>198111</enddate><creator>Gan‐Elepano, Minerva</creator><creator>Aeberhard, Ernesto</creator><creator>Mead, James F.</creator><general>Springer‐Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>198111</creationdate><title>On the mechanisms of fatty acid transformations in membranes</title><author>Gan‐Elepano, Minerva ; Aeberhard, Ernesto ; Mead, James F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3540-c4519c0a69f9bc4c0c61817fd1d552fbdaae6bfe7f114cda760c5e7a497b41ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Albumins - pharmacology</topic><topic>Animals</topic><topic>Arachidonic Acid</topic><topic>Arachidonic Acids - metabolism</topic><topic>Brain - metabolism</topic><topic>fatty acids</topic><topic>Fatty Acids - metabolism</topic><topic>Malonyl Coenzyme A - metabolism</topic><topic>Membrane Lipids - metabolism</topic><topic>Microsomes - metabolism</topic><topic>Rats</topic><topic>transformation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gan‐Elepano, Minerva</creatorcontrib><creatorcontrib>Aeberhard, Ernesto</creatorcontrib><creatorcontrib>Mead, James F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gan‐Elepano, Minerva</au><au>Aeberhard, Ernesto</au><au>Mead, James F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>On the mechanisms of fatty acid transformations in membranes</atitle><jtitle>Lipids</jtitle><addtitle>Lipids</addtitle><date>1981-11</date><risdate>1981</risdate><volume>16</volume><issue>11</issue><spage>790</spage><epage>795</epage><pages>790-795</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>Concentrations of albumin in excess of 1% in the incubation mixture inhibited the elongation of added fatty acids and their incorporation into microsomal lipids whereas these reactions were not inhibited with endogenous microsomal membrane fatty acids. 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subjects | Albumins - pharmacology Animals Arachidonic Acid Arachidonic Acids - metabolism Brain - metabolism fatty acids Fatty Acids - metabolism Malonyl Coenzyme A - metabolism Membrane Lipids - metabolism Microsomes - metabolism Rats transformation |
title | On the mechanisms of fatty acid transformations in membranes |
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