Benign fibrous histiocytoma of bone. Light- and electron-microscopic observations

Case report of a patient with an unusual, rapidly growing bone tumor in the third and fourth cervical vertebrae. Histological and electron-microscopic investigations reveal a tumor composed of histiocytic cells, xanthomatous cells, giant cells of Touton type, and fibroblastic cells. No cellular feat...

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Veröffentlicht in:Journal of cancer research and clinical oncology 1981-09, Vol.101 (2), p.191-202
Hauptverfasser: Roessner, A, Immenkamp, M, Weidner, A, Hobik, H P, Grundmann, E
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container_title Journal of cancer research and clinical oncology
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creator Roessner, A
Immenkamp, M
Weidner, A
Hobik, H P
Grundmann, E
description Case report of a patient with an unusual, rapidly growing bone tumor in the third and fourth cervical vertebrae. Histological and electron-microscopic investigations reveal a tumor composed of histiocytic cells, xanthomatous cells, giant cells of Touton type, and fibroblastic cells. No cellular features of malignancy are observed. From its cytologic appearance the tumor has to be classified as a benign fibrous histiocytoma. Regarding its ultrastructural features, the tumor may not be distinguished from non-ossifying fibroma of bone, but its clinical pattern shows obvious differences of localization and growth potential. the term "benign fibrous histiocytoma of bone" is proposed for these tumors which must be differentiated from non-ossifying fibroma.
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subjects Adult
Cervical Vertebrae
Diagnosis, Differential
Fibroma - pathology
Fibroma - ultrastructure
Histiocytoma, Benign Fibrous - pathology
Histiocytoma, Benign Fibrous - ultrastructure
Humans
Male
Microscopy, Electron
Spinal Neoplasms - pathology
Spinal Neoplasms - ultrastructure
title Benign fibrous histiocytoma of bone. Light- and electron-microscopic observations
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