Platelet Aggregation Inhibitors. X. S-Substituted 2-Thioadenosines and Their Derivatives

A series of S-substituted 2-thioadenosines (IV) were prepared by treatment of 2-thioadenosine (III) with a requisite halide in NaOH-H2O, NaOH-H2O-EtOH, Na/dimeth-ylformamide, NaOMe/dimethylformamide or NaH/dimethylformamide. N-Substituted 2-aminoadenosines (V) were obtained by treatment of 2-chloroa...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1977/10/25, Vol.25(10), pp.2624-2637
Hauptverfasser:	KIKUGAWA, KIYOMI, SUEHIRO, HIDEO, AOKI, AKIJI
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacology Animals Depression, Chemical Humans In Vitro Techniques Platelet Aggregation - drug effects platelet aggregometer Rabbits Thionucleosides - pharmacology
Online-Zugang:	Volltext
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