Effects of monocyclic compounds on biomembranes

Monocyclic compounds with an aliphatic chain containing at least 2 carbon atoms, interact with biomembranes producing solubilization of proteins. Plasma membrane seems to be more sensitive than mitochondrial-lysosomal membrane to the damaging effects of these compounds. Studies on the structure-acti...

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Veröffentlicht in:	Biochemical pharmacology 1977-11, Vol.26 (22), p.2145-2149
Hauptverfasser:	Sgaragli, Giampietro, Della Corte, Laura, Rizzotti-Conti, Margherita, Giotti, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Animals Cell Membrane - drug effects Chemical Phenomena Chemistry Erythrocyte Membrane - drug effects Erythrocytes - metabolism Guinea Pigs Hemoglobins - metabolism Humans In Vitro Techniques L-Lactate Dehydrogenase - metabolism Lipid Metabolism Lysosomes - drug effects Lysosomes - metabolism Lysosomes - ultrastructure Membranes - drug effects Mitochondria, Liver - drug effects Mitochondria, Liver - metabolism Mitochondria, Liver - ultrastructure Proteins - metabolism Rats Species Specificity
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