Isolation of Epstein-Barr virus from cultured cells of a patient with Hodgkin's disease

The suspension lymphoblastoid cell line named ChSL-1 was established from the tumor node of a patient with Hodgkin's disease. The cells of this culture produce a virus with morphological and physicochemical properties of herpes viruses. Immunologic study of the isolated virus demonstrated great...

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Veröffentlicht in:	Experimentelle Pathologie 1977, Vol.13 (6), p.289-295
Hauptverfasser:	Agrba, V.Z., Djatchenko, A.G., Lapin, B.A., Sangulija, I.A., Yakovleva, L.A., Chuvirov, G.N., Kokosha, L.V., Markova, T.P., Kakubava, V.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Antibodies, Viral Burkitt Lymphoma - immunology Burkitt's lymphoma cell culture Cells, Cultured Centrifugation, Density Gradient Cricetinae Epstein-Barr virus established cell lines hamster herpes virus Herpesvirus 4, Human - immunology Herpesvirus 4, Human - isolation & purification Hodgkin Disease - microbiology Hodgkin Disease - ultrastructure Hodgkin's disease Humans immunofluorescence immunoglobulins lymphoblastoid cells lymphocyte lymphogranulomatosis Mice mouse nasopharyngeal carcinoma Nasopharyngeal Neoplasms - immunology
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Zusammenfassung:	The suspension lymphoblastoid cell line named ChSL-1 was established from the tumor node of a patient with Hodgkin's disease. The cells of this culture produce a virus with morphological and physicochemical properties of herpes viruses. Immunologic study of the isolated virus demonstrated great similarity with the Epstein-Barr virus (EBV).
ISSN:	0014-4908
DOI:	10.1016/S0014-4908(77)80015-X