Alterations of plasma lipid and lipoprotein levels associated with benzodiazepine use The LRC program prevalence study
In a study of white adults from 10 North American Lipid Research Clinics populations, plasma lipid and lipoprotein levels in benzodiazepine (diazepam, chlordiazepoxide, flurazepam) users were compared to both the entire population of non-users and matched control non-users. Significantly higher plas...
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| Veröffentlicht in: | Atherosclerosis 1981-10, Vol.40 (2), p.159-165 |
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| container_end_page | 165 |
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| container_title | Atherosclerosis |
| container_volume | 40 |
| creator | Hunninghake, Donald Wallace, Robert B. Reiland, Susan Barrett-Connor, Elizabeth Wahl, Patricia Hoover, Joanne Heiss, Gerardo |
| description | In a study of white adults from 10 North American Lipid Research Clinics populations, plasma lipid and lipoprotein levels in benzodiazepine (diazepam, chlordiazepoxide, flurazepam) users were compared to both the entire population of non-users and matched control non-users. Significantly higher plasma triglyceride and very low density lipoprotein cholesterol levels and by one method of analysis, lower high density lipoprotein cholesterol levels were noted in male benzodiazepine users. No significant differences were noted in total plasma cholesterol or low density lipoprotein cholesterol levels. |
| doi_str_mv | 10.1016/0021-9150(81)90034-4 |
| format | Article |
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Significantly higher plasma triglyceride and very low density lipoprotein cholesterol levels and by one method of analysis, lower high density lipoprotein cholesterol levels were noted in male benzodiazepine users. No significant differences were noted in total plasma cholesterol or low density lipoprotein cholesterol levels.</description><identifier>ISSN: 0021-9150</identifier><identifier>EISSN: 1879-1484</identifier><identifier>DOI: 10.1016/0021-9150(81)90034-4</identifier><identifier>PMID: 6118165</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Anti-Anxiety Agents - pharmacology ; Benzodiazepines ; Chlordiazepoxide ; Cholesterol ; Cholesterol - blood ; Diazepam ; Female ; Flurazepam ; High density lipoprotein ; Humans ; Lipids ; Lipids - blood ; Lipoproteins ; Lipoproteins - blood ; Male ; Middle Aged ; Triglycerides ; Triglycerides - blood ; Very low density lipoprotein</subject><ispartof>Atherosclerosis, 1981-10, Vol.40 (2), p.159-165</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-9be5b0847241c3b2c9b2ca714909c878491086f2debd6f4bec30d5277427541a3</citedby><cites>FETCH-LOGICAL-c357t-9be5b0847241c3b2c9b2ca714909c878491086f2debd6f4bec30d5277427541a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0021-9150(81)90034-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6118165$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hunninghake, Donald</creatorcontrib><creatorcontrib>Wallace, Robert B.</creatorcontrib><creatorcontrib>Reiland, Susan</creatorcontrib><creatorcontrib>Barrett-Connor, Elizabeth</creatorcontrib><creatorcontrib>Wahl, Patricia</creatorcontrib><creatorcontrib>Hoover, Joanne</creatorcontrib><creatorcontrib>Heiss, Gerardo</creatorcontrib><creatorcontrib>Medication and hormones working group</creatorcontrib><title>Alterations of plasma lipid and lipoprotein levels associated with benzodiazepine use The LRC program prevalence study</title><title>Atherosclerosis</title><addtitle>Atherosclerosis</addtitle><description>In a study of white adults from 10 North American Lipid Research Clinics populations, plasma lipid and lipoprotein levels in benzodiazepine (diazepam, chlordiazepoxide, flurazepam) users were compared to both the entire population of non-users and matched control non-users. Significantly higher plasma triglyceride and very low density lipoprotein cholesterol levels and by one method of analysis, lower high density lipoprotein cholesterol levels were noted in male benzodiazepine users. No significant differences were noted in total plasma cholesterol or low density lipoprotein cholesterol levels.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Anti-Anxiety Agents - pharmacology</subject><subject>Benzodiazepines</subject><subject>Chlordiazepoxide</subject><subject>Cholesterol</subject><subject>Cholesterol - blood</subject><subject>Diazepam</subject><subject>Female</subject><subject>Flurazepam</subject><subject>High density lipoprotein</subject><subject>Humans</subject><subject>Lipids</subject><subject>Lipids - blood</subject><subject>Lipoproteins</subject><subject>Lipoproteins - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Triglycerides</subject><subject>Triglycerides - blood</subject><subject>Very low density lipoprotein</subject><issn>0021-9150</issn><issn>1879-1484</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kFGL1TAQhYMo693Vf6CQJ9GHaqZJm_RFWC66ChcEWZ9DmkzdSNrUJL3L7q-35V720YfhDMw5M8NHyBtgH4FB-4mxGqoOGvZewYeOMS4q8YzsQMmuAqHEc7J7srwklzn_YYwJCeqCXLQACtpmR47XoWAyxccp0zjQOZg8Ghr87B01k9u6OKdY0E804BFDpibnaL0p6Oi9L3e0x-kxOm8ecfYT0iUjvb1Devi5p2vydzLjqng0ASeLNJfFPbwiLwYTMr4-6xX59fXL7f5bdfhx831_fagsb2Spuh6bnikhawGW97Xt1jISRMc6q6QSHTDVDrXD3rWD6NFy5ppaSlHLRoDhV-Tdae_6yN8Fc9GjzxZDMBPGJWvJJedcitUoTkabYs4JBz0nP5r0oIHpDbfeWOqNpVarbrj1Fnt73r_0I7qn0JnvOv98mq_c8Ogx6Wz9hsH5hLZoF_3_D_wDZWqQDg</recordid><startdate>198110</startdate><enddate>198110</enddate><creator>Hunninghake, Donald</creator><creator>Wallace, Robert B.</creator><creator>Reiland, Susan</creator><creator>Barrett-Connor, Elizabeth</creator><creator>Wahl, Patricia</creator><creator>Hoover, Joanne</creator><creator>Heiss, Gerardo</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198110</creationdate><title>Alterations of plasma lipid and lipoprotein levels associated with benzodiazepine use The LRC program prevalence study</title><author>Hunninghake, Donald ; Wallace, Robert B. ; Reiland, Susan ; Barrett-Connor, Elizabeth ; Wahl, Patricia ; Hoover, Joanne ; Heiss, Gerardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-9be5b0847241c3b2c9b2ca714909c878491086f2debd6f4bec30d5277427541a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Anti-Anxiety Agents - pharmacology</topic><topic>Benzodiazepines</topic><topic>Chlordiazepoxide</topic><topic>Cholesterol</topic><topic>Cholesterol - blood</topic><topic>Diazepam</topic><topic>Female</topic><topic>Flurazepam</topic><topic>High density lipoprotein</topic><topic>Humans</topic><topic>Lipids</topic><topic>Lipids - blood</topic><topic>Lipoproteins</topic><topic>Lipoproteins - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Triglycerides</topic><topic>Triglycerides - blood</topic><topic>Very low density lipoprotein</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hunninghake, Donald</creatorcontrib><creatorcontrib>Wallace, Robert B.</creatorcontrib><creatorcontrib>Reiland, Susan</creatorcontrib><creatorcontrib>Barrett-Connor, Elizabeth</creatorcontrib><creatorcontrib>Wahl, Patricia</creatorcontrib><creatorcontrib>Hoover, Joanne</creatorcontrib><creatorcontrib>Heiss, Gerardo</creatorcontrib><creatorcontrib>Medication and hormones working group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Atherosclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hunninghake, Donald</au><au>Wallace, Robert B.</au><au>Reiland, Susan</au><au>Barrett-Connor, Elizabeth</au><au>Wahl, Patricia</au><au>Hoover, Joanne</au><au>Heiss, Gerardo</au><aucorp>Medication and hormones working group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alterations of plasma lipid and lipoprotein levels associated with benzodiazepine use The LRC program prevalence study</atitle><jtitle>Atherosclerosis</jtitle><addtitle>Atherosclerosis</addtitle><date>1981-10</date><risdate>1981</risdate><volume>40</volume><issue>2</issue><spage>159</spage><epage>165</epage><pages>159-165</pages><issn>0021-9150</issn><eissn>1879-1484</eissn><abstract>In a study of white adults from 10 North American Lipid Research Clinics populations, plasma lipid and lipoprotein levels in benzodiazepine (diazepam, chlordiazepoxide, flurazepam) users were compared to both the entire population of non-users and matched control non-users. Significantly higher plasma triglyceride and very low density lipoprotein cholesterol levels and by one method of analysis, lower high density lipoprotein cholesterol levels were noted in male benzodiazepine users. No significant differences were noted in total plasma cholesterol or low density lipoprotein cholesterol levels.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>6118165</pmid><doi>10.1016/0021-9150(81)90034-4</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-9150 |
| ispartof | Atherosclerosis, 1981-10, Vol.40 (2), p.159-165 |
| issn | 0021-9150 1879-1484 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adult Age Factors Aged Anti-Anxiety Agents - pharmacology Benzodiazepines Chlordiazepoxide Cholesterol Cholesterol - blood Diazepam Female Flurazepam High density lipoprotein Humans Lipids Lipids - blood Lipoproteins Lipoproteins - blood Male Middle Aged Triglycerides Triglycerides - blood Very low density lipoprotein |
| title | Alterations of plasma lipid and lipoprotein levels associated with benzodiazepine use The LRC program prevalence study |
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