Anti-tumor Activity of Eighty Four Synthesized N-Heteroaromatic Compounds

Eighty-four compounds (mainly N-heteroaromatic compounds) were synthesized and their antitumor activity was examined. Four quinoline derivatives were found to have some antitumor effect on the solid type of Ehrlich carcinoma. These compounds were, 3-hydroxy-6-quinolinecarbonitrile (sample No. 7-III)...

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Veröffentlicht in:	YAKUGAKU ZASSHI 1977/09/25, Vol.97(9), pp.1022-1033
Hauptverfasser:	HAYASHI, EISAKU, HIGASHINO, TAKEO, IIJIMA, CHIHOKO, OISHI, ETSUO, MAKINO, HIROKAZU, IRIE, TOSHIO, YAMAMOTO, FUSAKO, YOKOYAMA, YOKO, IWAI, YOSHIHISA, KATO, HIROAKI, SHIMADA, NORIAKI, SUZUKI, SENJI, SONE, SHIGEHISA, MORIKAWA, KAZUKO, MOCHIZUKI, HIDEO, MIYASHITA, AKIRA, MORIKAWA, TEIKO, IINUMA, MITSUHISA, TOMITA, EIKO, OHKUMA, MIHOKO, SHINODA, HIROTAKA, KOHNO, MORIHIRO, MIZUNO, DENICHI
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Animals anti-tumor activity Antineoplastic Agents - chemical synthesis Drug Evaluation, Preclinical Ehrlich carcinoma furo [2, 3-d] pyrimidine Heterocyclic Compounds - chemical synthesis Heterocyclic Compounds - pharmacology imidazo [4, 5-b] pyrimidine isoquinoline Mice naphthyridine pyrazolo [3, 4-d] pyrimidine pyrido [2, 3-d] pyrimidine quinoline quinoxaline
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