AN EPIDEMIOLOGIC STUDY OF EPITHELIAL CARCINOMA OF THE OVARY
A case-control study to identify risk factors for epithelial ovarian cancer was undertaken among women in the age group 45–74 years who had been admitted to seven hospitals in Connecticut between July, 1977, and March, 1979. Characteristics that were found to increase the risk of epithelial ovarian...
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Veröffentlicht in: | American journal of epidemiology 1981-09, Vol.114 (3), p.398-405 |
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creator | HILDRETH, NANCY G. KELSEY, JENNIFER L. LIVOLSI, VIRGINIA A. FISCHER, DIANA B. HOLFORD, THEODORE R. MOSTOW, EVELYN D. SCHWARTZ, PETER E. WHITE, COLIN |
description | A case-control study to identify risk factors for epithelial ovarian cancer was undertaken among women in the age group 45–74 years who had been admitted to seven hospitals in Connecticut between July, 1977, and March, 1979. Characteristics that were found to increase the risk of epithelial ovarian cancer included being white, never having been pregnant, having a late age at menopause, having a family history of cancer of the ovary or endometrium, and having a long estimated number of years of ovulation. Prior use of post-menopausal estrogens did not alter the risk for epithelial ovarian cancer, but there was some indication that oral contraceptives protect against ovarian cancer. Women with ovarian cancer were somewhat more likely to have had a history of an underactive thyroid and were somewhat less likely to have had a history of an overactive thyroid than controls, although these trends were not statistically significant. |
doi_str_mv | 10.1093/oxfordjournals.aje.a113207 |
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Characteristics that were found to increase the risk of epithelial ovarian cancer included being white, never having been pregnant, having a late age at menopause, having a family history of cancer of the ovary or endometrium, and having a long estimated number of years of ovulation. Prior use of post-menopausal estrogens did not alter the risk for epithelial ovarian cancer, but there was some indication that oral contraceptives protect against ovarian cancer. Women with ovarian cancer were somewhat more likely to have had a history of an underactive thyroid and were somewhat less likely to have had a history of an overactive thyroid than controls, although these trends were not statistically significant.</description><identifier>ISSN: 0002-9262</identifier><identifier>EISSN: 1476-6256</identifier><identifier>DOI: 10.1093/oxfordjournals.aje.a113207</identifier><identifier>PMID: 7304575</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Aged ; Carcinoma - epidemiology ; Carcinoma - etiology ; Carcinoma - genetics ; Connecticut ; estrogens ; Estrogens - adverse effects ; Female ; Humans ; Menopause ; Menstruation ; Middle Aged ; ovarian neoplasms ; Ovarian Neoplasms - epidemiology ; Ovarian Neoplasms - etiology ; Ovarian Neoplasms - genetics ; Population ; Risk ; Surveys and Questionnaires</subject><ispartof>American journal of epidemiology, 1981-09, Vol.114 (3), p.398-405</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c380t-e15eddc861cbc94ac5bd05bc46c255a4cc98b09dd6a5323c3361bc8a92cc95913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27869,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7304575$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HILDRETH, NANCY G.</creatorcontrib><creatorcontrib>KELSEY, JENNIFER L.</creatorcontrib><creatorcontrib>LIVOLSI, VIRGINIA A.</creatorcontrib><creatorcontrib>FISCHER, DIANA B.</creatorcontrib><creatorcontrib>HOLFORD, THEODORE R.</creatorcontrib><creatorcontrib>MOSTOW, EVELYN D.</creatorcontrib><creatorcontrib>SCHWARTZ, PETER E.</creatorcontrib><creatorcontrib>WHITE, COLIN</creatorcontrib><title>AN EPIDEMIOLOGIC STUDY OF EPITHELIAL CARCINOMA OF THE OVARY</title><title>American journal of epidemiology</title><addtitle>Am J Epidemiol</addtitle><description>A case-control study to identify risk factors for epithelial ovarian cancer was undertaken among women in the age group 45–74 years who had been admitted to seven hospitals in Connecticut between July, 1977, and March, 1979. Characteristics that were found to increase the risk of epithelial ovarian cancer included being white, never having been pregnant, having a late age at menopause, having a family history of cancer of the ovary or endometrium, and having a long estimated number of years of ovulation. Prior use of post-menopausal estrogens did not alter the risk for epithelial ovarian cancer, but there was some indication that oral contraceptives protect against ovarian cancer. 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Characteristics that were found to increase the risk of epithelial ovarian cancer included being white, never having been pregnant, having a late age at menopause, having a family history of cancer of the ovary or endometrium, and having a long estimated number of years of ovulation. Prior use of post-menopausal estrogens did not alter the risk for epithelial ovarian cancer, but there was some indication that oral contraceptives protect against ovarian cancer. Women with ovarian cancer were somewhat more likely to have had a history of an underactive thyroid and were somewhat less likely to have had a history of an overactive thyroid than controls, although these trends were not statistically significant.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>7304575</pmid><doi>10.1093/oxfordjournals.aje.a113207</doi><tpages>8</tpages></addata></record> |
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subjects | Aged Carcinoma - epidemiology Carcinoma - etiology Carcinoma - genetics Connecticut estrogens Estrogens - adverse effects Female Humans Menopause Menstruation Middle Aged ovarian neoplasms Ovarian Neoplasms - epidemiology Ovarian Neoplasms - etiology Ovarian Neoplasms - genetics Population Risk Surveys and Questionnaires |
title | AN EPIDEMIOLOGIC STUDY OF EPITHELIAL CARCINOMA OF THE OVARY |
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