Diastereoisomers of 5,10-methylene-5,6,7,8-tetrahydropteroyl-D-glutamic acid

The diastereoisomers of 5,10-methylene 5,6,7,8-tetrahydropteroyl-D-glutamate were resolved and tested as substrates and inhibitors of Lactobacillus casei thymidylate synthetase. No activity was observed. The compounds were neither growth factors nor inhibitors for Lactobacillus casei, Streptococcus...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of medicinal chemistry 1977-11, Vol.20 (11), p.1531-1533
Hauptverfasser:	Kisliuk, R. L, Strumpf, D, Gaumont, Y, Leary, R. P, Plante, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Lactobacillus casei - drug effects Lactobacillus casei - enzymology Molecular Conformation Pediococcus - drug effects Stereoisomerism Streptococcus - drug effects Structure-Activity Relationship Tetrahydrofolates - metabolism Tetrahydrofolates - pharmacology Thymidylate Synthase - antagonists & inhibitors Thymidylate Synthase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!