Lysosomal enzyme release during cardiopulmonary bypass
Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefor...
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| Veröffentlicht in: | Anaesthesia 1977-09, Vol.32 (8), p.743-748 |
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| container_end_page | 748 |
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| container_issue | 8 |
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| container_title | Anaesthesia |
| container_volume | 32 |
| creator | GNANADURAI, T.V. BRANTHWAITE, M.A. COLBECK, J.F. WELMAN, E. |
| description | Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure. |
| doi_str_mv | 10.1111/j.1365-2044.1977.tb10074.x |
| format | Article |
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The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.</description><identifier>ISSN: 0003-2409</identifier><identifier>EISSN: 1365-2044</identifier><identifier>DOI: 10.1111/j.1365-2044.1977.tb10074.x</identifier><identifier>PMID: 920915</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Acetylglucosaminidase - blood ; Adolescent ; Adult ; Aged ; Cardiopulmonary Bypass ; Child ; Glucuronidase - blood ; Humans ; Lysosomes - enzymology ; METABOLISM; lysosomal enzymes ; Middle Aged ; SURGERY; cardiovascular ; Time Factors</subject><ispartof>Anaesthesia, 1977-09, Vol.32 (8), p.743-748</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4503-9cf222ecbc84d7cf1c6add41b1aaf41fa7e8a87cd477bb5f632d6155a9ccc5163</citedby><cites>FETCH-LOGICAL-c4503-9cf222ecbc84d7cf1c6add41b1aaf41fa7e8a87cd477bb5f632d6155a9ccc5163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2044.1977.tb10074.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2044.1977.tb10074.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/920915$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>GNANADURAI, T.V.</creatorcontrib><creatorcontrib>BRANTHWAITE, M.A.</creatorcontrib><creatorcontrib>COLBECK, J.F.</creatorcontrib><creatorcontrib>WELMAN, E.</creatorcontrib><title>Lysosomal enzyme release during cardiopulmonary bypass</title><title>Anaesthesia</title><addtitle>Anaesthesia</addtitle><description>Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.</description><subject>Acetylglucosaminidase - blood</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Cardiopulmonary Bypass</subject><subject>Child</subject><subject>Glucuronidase - blood</subject><subject>Humans</subject><subject>Lysosomes - enzymology</subject><subject>METABOLISM; lysosomal enzymes</subject><subject>Middle Aged</subject><subject>SURGERY; cardiovascular</subject><subject>Time Factors</subject><issn>0003-2409</issn><issn>1365-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkMlOwzAQhi3EVgpvwCHiwC3B43hJuKCqKotUwQXOlmM7KFU27EZteHoSpeqduczhX2b0IXQHOIJhHjYRxJyFBFMaQSpEtM0AY0Gj_QmaHaVTNMMYxyGhOL1EV95vMAaSQHKBzlOCU2AzxNe9b3xTqTKw9W9f2cDZ0ipvA9O5ov4OtHKmaNqurJpauT7I-lZ5f43OclV6e3PYc_T1vPpcvobrj5e35WIdasqGy6nOCSFWZzqhRugcNFfGUMhAqZxCroRNVCK0oUJkGct5TAwHxlSqtWbA4zm6n3pb1_x01m9lVXhty1LVtum8FLEAoJwNxsfJqF3jvbO5bF1RDQ9LwHJkJjdyBCNHMHJkJg_M5H4I3x6udFllzTE6QRrkp0neFaXt_1EsF--LlaBx_AcHz31q</recordid><startdate>197709</startdate><enddate>197709</enddate><creator>GNANADURAI, T.V.</creator><creator>BRANTHWAITE, M.A.</creator><creator>COLBECK, J.F.</creator><creator>WELMAN, E.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197709</creationdate><title>Lysosomal enzyme release during cardiopulmonary bypass</title><author>GNANADURAI, T.V. ; BRANTHWAITE, M.A. ; COLBECK, J.F. ; WELMAN, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4503-9cf222ecbc84d7cf1c6add41b1aaf41fa7e8a87cd477bb5f632d6155a9ccc5163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Acetylglucosaminidase - blood</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Cardiopulmonary Bypass</topic><topic>Child</topic><topic>Glucuronidase - blood</topic><topic>Humans</topic><topic>Lysosomes - enzymology</topic><topic>METABOLISM; lysosomal enzymes</topic><topic>Middle Aged</topic><topic>SURGERY; cardiovascular</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>GNANADURAI, T.V.</creatorcontrib><creatorcontrib>BRANTHWAITE, M.A.</creatorcontrib><creatorcontrib>COLBECK, J.F.</creatorcontrib><creatorcontrib>WELMAN, E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anaesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>GNANADURAI, T.V.</au><au>BRANTHWAITE, M.A.</au><au>COLBECK, J.F.</au><au>WELMAN, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lysosomal enzyme release during cardiopulmonary bypass</atitle><jtitle>Anaesthesia</jtitle><addtitle>Anaesthesia</addtitle><date>1977-09</date><risdate>1977</risdate><volume>32</volume><issue>8</issue><spage>743</spage><epage>748</epage><pages>743-748</pages><issn>0003-2409</issn><eissn>1365-2044</eissn><abstract>Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>920915</pmid><doi>10.1111/j.1365-2044.1977.tb10074.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2409 |
| ispartof | Anaesthesia, 1977-09, Vol.32 (8), p.743-748 |
| issn | 0003-2409 1365-2044 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73711465 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Acetylglucosaminidase - blood Adolescent Adult Aged Cardiopulmonary Bypass Child Glucuronidase - blood Humans Lysosomes - enzymology METABOLISM lysosomal enzymes Middle Aged SURGERY cardiovascular Time Factors |
| title | Lysosomal enzyme release during cardiopulmonary bypass |
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