Compensatory increase in synaptosomal aldehyde reductase activity in rat brain after chronic barbital treatment

The changes in brain aldehyde reductase (AIR) activities during long-term treatment of rats with barbital were studied. NADH-linked AIR activity in the synaptosomal fraction increased rapidly, and supernatant AIR activity rose later during barbital treatment. With respect to NADPH-linked AIR, two di...

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Veröffentlicht in:	Biochemical pharmacology 1981-10, Vol.30 (19), p.2657-2662
Hauptverfasser:	Minegishi, Akemi, Fukumori, Ryuji, Satoh, Tetsuo, Kitagawa, Haruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Oxidoreductases - metabolism Animals Barbital - pharmacology Barbiturates - pharmacology Brain - enzymology In Vitro Techniques Kinetics Male NADP - metabolism Rats Rats, Inbred Strains Synaptosomes - enzymology Time Factors
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