Metabolism of 14C‐Antipyrine in Suspensions of Isolated Rat Liver Cells

Suspensions of liver cells isolated from perfused rat livers were incubated with antipyrine‐N‐methyl‐14C. Antipyrine was eliminated by first‐order kinetics during incubations for 3 hours with primary suspensions (parenchymal cells + non‐parenchymal cells) and suspensions of purified parenchymal cell...

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Veröffentlicht in:	Acta pharmacologica et toxicologica 1977-09, Vol.41 (3), p.225-234
Hauptverfasser:	Aarbakke, Jarle, Bessesen, Atle, Marland, Jarg
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipyrine Antipyrine - metabolism cells Cells, Cultured Culture Media drug interactions drug metabolism Half-Life isolated liver Liver - cytology Liver - metabolism Male rat Rats Rats, Inbred Strains Time Factors
Online-Zugang:	Volltext
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