Synthesis of CDP-diglyceride from phosphatidylinositol and CMP
A reaction in which CDP-diglyceride and inositol are formed from 1-stearoyl, 2-arachidonoyl phosphatidylinositol and CMP occurs readily in dialyzed microsomal preparations from the mouse pancreas. The reaction is Mn 2+-dependent, and it is inhibited by each of the two products, CDP-diglyceride and m...
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| Veröffentlicht in: | Biochemical and biophysical research communications 1977-09, Vol.78 (1), p.364-371 |
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| container_end_page | 371 |
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| container_title | Biochemical and biophysical research communications |
| container_volume | 78 |
| creator | Hokin-Neaverson, Mabel Sadeghian, Kenneth Harris, Douglas W. Merrin, James S. |
| description | A reaction in which CDP-diglyceride and inositol are formed from 1-stearoyl, 2-arachidonoyl phosphatidylinositol and CMP occurs readily in dialyzed microsomal preparations from the mouse pancreas. The reaction is Mn
2+-dependent, and it is inhibited by each of the two products, CDP-diglyceride and myoinositol. It is presumed to involve the back-reaction of CDP-diglyceride: inositol phosphatidyltransferase (phosphatidyl-inositol synthetase, EC.2.7.8.11.) |
| doi_str_mv | 10.1016/0006-291X(77)91263-3 |
| format | Article |
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2+-dependent, and it is inhibited by each of the two products, CDP-diglyceride and myoinositol. It is presumed to involve the back-reaction of CDP-diglyceride: inositol phosphatidyltransferase (phosphatidyl-inositol synthetase, EC.2.7.8.11.)</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>907686</pmid><doi>10.1016/0006-291X(77)91263-3</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-291X |
| ispartof | Biochemical and biophysical research communications, 1977-09, Vol.78 (1), p.364-371 |
| issn | 0006-291X 1090-2104 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Cytidine Diphosphate Diglycerides - biosynthesis Cytidine Monophosphate - metabolism Cytosine Nucleotides - metabolism Magnesium - pharmacology Manganese - pharmacology Mice Microsomes - metabolism Nucleoside Diphosphate Sugars - biosynthesis Pancreas - metabolism Phosphatidylinositols - metabolism Phosphotransferases - metabolism Ribonucleotides - pharmacology |
| title | Synthesis of CDP-diglyceride from phosphatidylinositol and CMP |
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