Effects of Retinoic Acid and Other Retinoids on the Growth and Differentiation of 3T3 Supported Human Keratinocytes

Using mitomycin C treated 3T3-Swiss fibroblasts as feeder cells, human keratinocytes derived from infant foreskins were subcultured in the presence of trans-retinoic acid (RA) and other retinoids. At$1 \mu g/ml (3 \times 10^{-6} M)$and higher RA concentrations plating efficiency was markedly reduced...

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