Use of indium-111-labeled autologous leukocytes in differentiating pancreatic abscess from pseudocyst
Pancreatic abscess is very difficult to diagnose and to differentiate from pancreatic pseudocyst based on clinical findings, laboratory studies and roentgenographic examinations. Eight patients diagnosed as having a pancreatic mass by ultrasonography or computed tomography also underwent indium-111-...
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| Veröffentlicht in: | Am. J. Surg.; (United States) 1981-09, Vol.142 (3), p.312-316 |
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| creator | Bicknell, Teresa A. Kohatsu, Shoichi Goodwin, David A. |
| description | Pancreatic abscess is very difficult to diagnose and to differentiate from pancreatic pseudocyst based on clinical findings, laboratory studies and roentgenographic examinations. Eight patients diagnosed as having a pancreatic mass by ultrasonography or computed tomography also underwent indium-111-labeled autologous leukocyte scanning (10 scans) for suspected intraabdominal sepsis. This scan detects migration of labeled leukocytes into abscesses or areas of inflammation. Four patients had abscess and positive scans, and four patients had pseudocyst and negative scans. There was one false-positive scan in a patient with a recurrent pancreatic mass after drainage of an abscess. Since pancreatic abscess requires prompt drainage, and since it may be preferable to delay drainage of a pseudocyst, the differentiation of these two conditions is important. This test appears very effective in diagnosing pancreatic abscess and differentiating it from a pseudocyst. |
| doi_str_mv | 10.1016/0002-9610(81)90337-8 |
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Eight patients diagnosed as having a pancreatic mass by ultrasonography or computed tomography also underwent indium-111-labeled autologous leukocyte scanning (10 scans) for suspected intraabdominal sepsis. This scan detects migration of labeled leukocytes into abscesses or areas of inflammation. Four patients had abscess and positive scans, and four patients had pseudocyst and negative scans. There was one false-positive scan in a patient with a recurrent pancreatic mass after drainage of an abscess. Since pancreatic abscess requires prompt drainage, and since it may be preferable to delay drainage of a pseudocyst, the differentiation of these two conditions is important. This test appears very effective in diagnosing pancreatic abscess and differentiating it from a pseudocyst.</description><identifier>ISSN: 0002-9610</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/0002-9610(81)90337-8</identifier><identifier>PMID: 7283019</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; 550901 - Pathology- Tracer Techniques ; Abscess - diagnostic imaging ; ABSCESSES ; BASIC BIOLOGICAL SCIENCES ; BETA DECAY RADIOISOTOPES ; BIOLOGICAL LOCALIZATION ; BIOLOGICAL MATERIALS ; BLOOD ; BLOOD CELLS ; BODY ; BODY FLUIDS ; COUNTING TECHNIQUES ; DAYS LIVING RADIOISOTOPES ; DIAGNOSIS ; Diagnosis, Differential ; DIAGNOSTIC TECHNIQUES ; DIAGNOSTIC USES ; DIGESTIVE SYSTEM ; ELECTRON CAPTURE RADIOISOTOPES ; ENDOCRINE GLANDS ; False Negative Reactions ; GLANDS ; Humans ; Indium ; INDIUM 111 ; INDIUM ISOTOPES ; INFLAMMATION ; INTERMEDIATE MASS NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; LABELLED COMPOUNDS ; LEUKOCYTES ; MATERIALS ; MINUTES LIVING RADIOISOTOPES ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANS ; PANCREAS ; Pancreatic Cyst - diagnostic imaging ; Pancreatic Diseases - diagnostic imaging ; Pancreatic Pseudocyst - diagnostic imaging ; PATHOLOGICAL CHANGES ; PATIENTS ; RADIOISOTOPE SCANNING ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; SCINTISCANNING ; SYMPTOMS ; USES</subject><ispartof>Am. 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Surg.; (United States), 1981-09, Vol.142 (3), p.312-316</ispartof><rights>1981</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-92f8ecef7144e32be2e9174b1a68ded0c15c5e43fddb6318113ae04222a55cfd3</citedby><cites>FETCH-LOGICAL-c415t-92f8ecef7144e32be2e9174b1a68ded0c15c5e43fddb6318113ae04222a55cfd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9610(81)90337-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,885,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7283019$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/5346222$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Bicknell, Teresa A.</creatorcontrib><creatorcontrib>Kohatsu, Shoichi</creatorcontrib><creatorcontrib>Goodwin, David A.</creatorcontrib><title>Use of indium-111-labeled autologous leukocytes in differentiating pancreatic abscess from pseudocyst</title><title>Am. J. Surg.; (United States)</title><addtitle>Am J Surg</addtitle><description>Pancreatic abscess is very difficult to diagnose and to differentiate from pancreatic pseudocyst based on clinical findings, laboratory studies and roentgenographic examinations. Eight patients diagnosed as having a pancreatic mass by ultrasonography or computed tomography also underwent indium-111-labeled autologous leukocyte scanning (10 scans) for suspected intraabdominal sepsis. This scan detects migration of labeled leukocytes into abscesses or areas of inflammation. Four patients had abscess and positive scans, and four patients had pseudocyst and negative scans. There was one false-positive scan in a patient with a recurrent pancreatic mass after drainage of an abscess. Since pancreatic abscess requires prompt drainage, and since it may be preferable to delay drainage of a pseudocyst, the differentiation of these two conditions is important. This test appears very effective in diagnosing pancreatic abscess and differentiating it from a pseudocyst.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>550901 - Pathology- Tracer Techniques</subject><subject>Abscess - diagnostic imaging</subject><subject>ABSCESSES</subject><subject>BASIC BIOLOGICAL SCIENCES</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BIOLOGICAL LOCALIZATION</subject><subject>BIOLOGICAL MATERIALS</subject><subject>BLOOD</subject><subject>BLOOD CELLS</subject><subject>BODY</subject><subject>BODY FLUIDS</subject><subject>COUNTING TECHNIQUES</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DIAGNOSIS</subject><subject>Diagnosis, Differential</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DIAGNOSTIC USES</subject><subject>DIGESTIVE SYSTEM</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>ENDOCRINE GLANDS</subject><subject>False Negative Reactions</subject><subject>GLANDS</subject><subject>Humans</subject><subject>Indium</subject><subject>INDIUM 111</subject><subject>INDIUM ISOTOPES</subject><subject>INFLAMMATION</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>LABELLED COMPOUNDS</subject><subject>LEUKOCYTES</subject><subject>MATERIALS</subject><subject>MINUTES LIVING RADIOISOTOPES</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANS</subject><subject>PANCREAS</subject><subject>Pancreatic Cyst - diagnostic imaging</subject><subject>Pancreatic Diseases - diagnostic imaging</subject><subject>Pancreatic Pseudocyst - diagnostic imaging</subject><subject>PATHOLOGICAL CHANGES</subject><subject>PATIENTS</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>SCINTISCANNING</subject><subject>SYMPTOMS</subject><subject>USES</subject><issn>0002-9610</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1TAQhS0EKreFNwApYoHKIsXjn8TZVEIVUKRK3dC15djjYkjii-1U6tvjcK-6hJXHmm-OfeYQ8gboBVDoPlJKWTt0QM8VfBgo532rnpEdqH5oQSn-nOyekJfkNOef9Qog-Ak56ZniFIYdwbuMTfRNWFxY5xYA2smMOKFrzFriFO_jmpsJ11_RPhbMFWxc8B4TLiWYEpb7Zm8Wm7DWtjFjtphz41Ocm33G1dWxXF6RF95MGV8fzzNy9-Xz96vr9ub267erTzetFSBLOzCv0KLvQQjkbESGA_RiBNMph45akFai4N65seOgALhBKhhjRkrrHT8j7w66MZegsw0F7Q8blwVt0ZKLrqIVen-A9in-XjEXPYf662kyC1azuudd34tO_RcEKblkTFZQHECbYs4Jvd6nMJv0qIHqLSu9BaG3ILQC_Tcrvem_Peqv44zuaegYTu1fHvpYV_YQMG2OcLHoQtoMuRj-_cAf-cyjrw</recordid><startdate>198109</startdate><enddate>198109</enddate><creator>Bicknell, Teresa A.</creator><creator>Kohatsu, Shoichi</creator><creator>Goodwin, David A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>198109</creationdate><title>Use of indium-111-labeled autologous leukocytes in differentiating pancreatic abscess from pseudocyst</title><author>Bicknell, Teresa A. ; Kohatsu, Shoichi ; Goodwin, David A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-92f8ecef7144e32be2e9174b1a68ded0c15c5e43fddb6318113ae04222a55cfd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>550901 - Pathology- Tracer Techniques</topic><topic>Abscess - diagnostic imaging</topic><topic>ABSCESSES</topic><topic>BASIC BIOLOGICAL SCIENCES</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BIOLOGICAL LOCALIZATION</topic><topic>BIOLOGICAL MATERIALS</topic><topic>BLOOD</topic><topic>BLOOD CELLS</topic><topic>BODY</topic><topic>BODY FLUIDS</topic><topic>COUNTING TECHNIQUES</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DIAGNOSIS</topic><topic>Diagnosis, Differential</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DIAGNOSTIC USES</topic><topic>DIGESTIVE SYSTEM</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>ENDOCRINE GLANDS</topic><topic>False Negative Reactions</topic><topic>GLANDS</topic><topic>Humans</topic><topic>Indium</topic><topic>INDIUM 111</topic><topic>INDIUM ISOTOPES</topic><topic>INFLAMMATION</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>LABELLED COMPOUNDS</topic><topic>LEUKOCYTES</topic><topic>MATERIALS</topic><topic>MINUTES LIVING RADIOISOTOPES</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANS</topic><topic>PANCREAS</topic><topic>Pancreatic Cyst - diagnostic imaging</topic><topic>Pancreatic Diseases - diagnostic imaging</topic><topic>Pancreatic Pseudocyst - diagnostic imaging</topic><topic>PATHOLOGICAL CHANGES</topic><topic>PATIENTS</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>SCINTISCANNING</topic><topic>SYMPTOMS</topic><topic>USES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bicknell, Teresa A.</creatorcontrib><creatorcontrib>Kohatsu, Shoichi</creatorcontrib><creatorcontrib>Goodwin, David A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Am. J. Surg.; (United States)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bicknell, Teresa A.</au><au>Kohatsu, Shoichi</au><au>Goodwin, David A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of indium-111-labeled autologous leukocytes in differentiating pancreatic abscess from pseudocyst</atitle><jtitle>Am. J. Surg.; (United States)</jtitle><addtitle>Am J Surg</addtitle><date>1981-09</date><risdate>1981</risdate><volume>142</volume><issue>3</issue><spage>312</spage><epage>316</epage><pages>312-316</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><abstract>Pancreatic abscess is very difficult to diagnose and to differentiate from pancreatic pseudocyst based on clinical findings, laboratory studies and roentgenographic examinations. Eight patients diagnosed as having a pancreatic mass by ultrasonography or computed tomography also underwent indium-111-labeled autologous leukocyte scanning (10 scans) for suspected intraabdominal sepsis. This scan detects migration of labeled leukocytes into abscesses or areas of inflammation. Four patients had abscess and positive scans, and four patients had pseudocyst and negative scans. There was one false-positive scan in a patient with a recurrent pancreatic mass after drainage of an abscess. Since pancreatic abscess requires prompt drainage, and since it may be preferable to delay drainage of a pseudocyst, the differentiation of these two conditions is important. This test appears very effective in diagnosing pancreatic abscess and differentiating it from a pseudocyst.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7283019</pmid><doi>10.1016/0002-9610(81)90337-8</doi><tpages>5</tpages></addata></record> |
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| issn | 0002-9610 1879-1883 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics 550901 - Pathology- Tracer Techniques Abscess - diagnostic imaging ABSCESSES BASIC BIOLOGICAL SCIENCES BETA DECAY RADIOISOTOPES BIOLOGICAL LOCALIZATION BIOLOGICAL MATERIALS BLOOD BLOOD CELLS BODY BODY FLUIDS COUNTING TECHNIQUES DAYS LIVING RADIOISOTOPES DIAGNOSIS Diagnosis, Differential DIAGNOSTIC TECHNIQUES DIAGNOSTIC USES DIGESTIVE SYSTEM ELECTRON CAPTURE RADIOISOTOPES ENDOCRINE GLANDS False Negative Reactions GLANDS Humans Indium INDIUM 111 INDIUM ISOTOPES INFLAMMATION INTERMEDIATE MASS NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES LABELLED COMPOUNDS LEUKOCYTES MATERIALS MINUTES LIVING RADIOISOTOPES NUCLEI ODD-EVEN NUCLEI ORGANS PANCREAS Pancreatic Cyst - diagnostic imaging Pancreatic Diseases - diagnostic imaging Pancreatic Pseudocyst - diagnostic imaging PATHOLOGICAL CHANGES PATIENTS RADIOISOTOPE SCANNING RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging SCINTISCANNING SYMPTOMS USES |
| title | Use of indium-111-labeled autologous leukocytes in differentiating pancreatic abscess from pseudocyst |
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