Different states of transplantation tolerance, and the problem of inheritance of tolerance

In agreement with previous results, we failed to observe hereditary transmission of transplantation tolerance in the progeny of tolerant male mice when tested by skin grafting. At the same time we showed that the detection of the tolerance state depended on the test of immunity used. The possibility...

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Veröffentlicht in:Immunology letters 1981-08, Vol.3 (3), p.183-186
Hauptverfasser: Hasek, M, Holán, V, Kousalová, M
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Holán, V
Kousalová, M
description In agreement with previous results, we failed to observe hereditary transmission of transplantation tolerance in the progeny of tolerant male mice when tested by skin grafting. At the same time we showed that the detection of the tolerance state depended on the test of immunity used. The possibility has not excluded that positive results with hereditary transmission of tolerance via fathers [1–3] may be due to the appropriate detection systems.
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subjects Animals
Cytotoxicity, Immunologic
Female
Graft Rejection
Immune Tolerance
Lymphocyte Culture Test, Mixed
Male
Mice
Mice, Inbred C57BL - genetics
Skin Transplantation
Spleen - transplantation
title Different states of transplantation tolerance, and the problem of inheritance of tolerance
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