Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight
We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery ov...
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| Veröffentlicht in: | Anesthesia and analgesia 2003-10, Vol.97 (4), p.958-963 |
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| creator | Scott, Bharathi H. Seifert, Frank C. Glass, Peter S. A. Grimson, Roger |
| description | We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a period of 2 yr (1999 and 2000); 681 patients underwent coronary surgery with use of CPB, and 554 patients underwent off-pump coronary artery bypass surgery using a median sternotomy incision. There were 881 males and 354 females. Average packed red blood cells (PRBC) transfusion for patients on CPB was 3.4 U compared with 1.6 U for the off-pump group (P = |
| doi_str_mv | 10.1213/01.ANE.0000081790.75298.D8 |
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A. ; Grimson, Roger</creator><creatorcontrib>Scott, Bharathi H. ; Seifert, Frank C. ; Glass, Peter S. A. ; Grimson, Roger</creatorcontrib><description><![CDATA[We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a period of 2 yr (1999 and 2000); 681 patients underwent coronary surgery with use of CPB, and 554 patients underwent off-pump coronary artery bypass surgery using a median sternotomy incision. There were 881 males and 354 females. Average packed red blood cells (PRBC) transfusion for patients on CPB was 3.4 U compared with 1.6 U for the off-pump group (P = <0.001). Patients on CPB received more frequent PRBC transfusion (72.5%) compared with 45.7% of off-pump patients (P = <0.001). Average PRBC transfusion for males was 2.2 U compared with 3.6 U for females (P = <0.001). A lower percentage of males (52.6%) than females (79.4%) received transfusion (P = <0.001). The impact of CPB, off-pump status, preoperative hematocrit <35%, gender, age ≥65 yr, and weight ≤83 kilograms using median values as cut points, on blood use was examined using logistic regression models. Use of CPB, preoperative hematocrit, (<35%) female gender, increasing age, and decreased body weight were significant predictors of transfusion (P = <0.001). Preoperative hematocrit <35% and use of CPB were the strongest predictors of PRBC transfusion.]]></description><identifier>ISSN: 0003-2999</identifier><identifier>EISSN: 1526-7598</identifier><identifier>DOI: 10.1213/01.ANE.0000081790.75298.D8</identifier><identifier>PMID: 14500140</identifier><identifier>CODEN: AACRAT</identifier><language>eng</language><publisher>Hagerstown, MD: International Anesthesia Research Society</publisher><subject>Adult ; Aged ; Aging - physiology ; Anesthesia ; Anesthesia depending on type of surgery ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Transfusion - statistics & numerical data ; Body Weight - physiology ; Cardiopulmonary Bypass - instrumentation ; Coronary Artery Bypass ; Databases, Factual ; Erythrocyte Transfusion ; Extracorporeal Circulation - adverse effects ; Extracorporeal Circulation - instrumentation ; Female ; Hematocrit ; Humans ; Male ; Medical sciences ; Middle Aged ; Prospective Studies ; Risk Factors ; Sex Characteristics ; Thoracic and cardiovascular surgery. Cardiopulmonary bypass</subject><ispartof>Anesthesia and analgesia, 2003-10, Vol.97 (4), p.958-963</ispartof><rights>International Anesthesia Research Society</rights><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4238-6fffc78555c8b0ff19fe2da97f37b070ccc02f7b3daaf4daa3f46da3cf8b63973</citedby><cites>FETCH-LOGICAL-c4238-6fffc78555c8b0ff19fe2da97f37b070ccc02f7b3daaf4daa3f46da3cf8b63973</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00000539-200310000-00008$$EHTML$$P50$$Gwolterskluwer$$H</linktohtml><link.rule.ids>314,776,780,4595,27901,27902,65206</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15164149$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14500140$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scott, Bharathi H.</creatorcontrib><creatorcontrib>Seifert, Frank C.</creatorcontrib><creatorcontrib>Glass, Peter S. A.</creatorcontrib><creatorcontrib>Grimson, Roger</creatorcontrib><title>Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight</title><title>Anesthesia and analgesia</title><addtitle>Anesth Analg</addtitle><description><![CDATA[We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a period of 2 yr (1999 and 2000); 681 patients underwent coronary surgery with use of CPB, and 554 patients underwent off-pump coronary artery bypass surgery using a median sternotomy incision. There were 881 males and 354 females. Average packed red blood cells (PRBC) transfusion for patients on CPB was 3.4 U compared with 1.6 U for the off-pump group (P = <0.001). Patients on CPB received more frequent PRBC transfusion (72.5%) compared with 45.7% of off-pump patients (P = <0.001). Average PRBC transfusion for males was 2.2 U compared with 3.6 U for females (P = <0.001). A lower percentage of males (52.6%) than females (79.4%) received transfusion (P = <0.001). The impact of CPB, off-pump status, preoperative hematocrit <35%, gender, age ≥65 yr, and weight ≤83 kilograms using median values as cut points, on blood use was examined using logistic regression models. Use of CPB, preoperative hematocrit, (<35%) female gender, increasing age, and decreased body weight were significant predictors of transfusion (P = <0.001). Preoperative hematocrit <35% and use of CPB were the strongest predictors of PRBC transfusion.]]></description><subject>Adult</subject><subject>Aged</subject><subject>Aging - physiology</subject><subject>Anesthesia</subject><subject>Anesthesia depending on type of surgery</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion - statistics & numerical data</subject><subject>Body Weight - physiology</subject><subject>Cardiopulmonary Bypass - instrumentation</subject><subject>Coronary Artery Bypass</subject><subject>Databases, Factual</subject><subject>Erythrocyte Transfusion</subject><subject>Extracorporeal Circulation - adverse effects</subject><subject>Extracorporeal Circulation - instrumentation</subject><subject>Female</subject><subject>Hematocrit</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Sex Characteristics</subject><subject>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</subject><issn>0003-2999</issn><issn>1526-7598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkdFu2yAUQNG0ac26_cKEJm1PsQcGG-hbknZtpWqttEV7RBiD4802Htiq8hf75JHaUnjgcsW594IOAJ8wSnGGyVeE0833mxSdFsdMoJTlmeDpNX8FVjjPioTlgr8Gq3hPkkwIcQHehfA7phjx4i24wDSPZ4pW4N-2da6C-2Bg08MnNTamHwPc95XxtWv6Gu6cd73yR7jxo4lhexxUCPDH5OuYXsH7blB6hI8W7pSvGjdMbTcXLOTT1A1reGc6NTrtm3ENb82p_RpuarOGqq_g1lVH-Ms09WF8D95Y1QbzYYmXYP_t5ufuLnl4vL3fbR4STTPCk8JaqxnP81zzElmLhTVZpQSzhJWIIa01yiwrSaWUpXEjlhaVItrysiCCkUvwZe47ePd3MmGUXRO0aVvVGzcFyUhRME5pBK9mUHsXgjdWDr7p4v8kRvLkQyIsow959iFffMhrHos_LlOmsjPVuXQREIHPC6CCVq31qtdNOHM5LiimInJ05p5dGzWEP-30bLw8GNWOh3l0TkSSReP4lCQvjyH_ARHZpSs</recordid><startdate>20031001</startdate><enddate>20031001</enddate><creator>Scott, Bharathi H.</creator><creator>Seifert, Frank C.</creator><creator>Glass, Peter S. A.</creator><creator>Grimson, Roger</creator><general>International Anesthesia Research Society</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20031001</creationdate><title>Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight</title><author>Scott, Bharathi H. ; Seifert, Frank C. ; Glass, Peter S. A. ; Grimson, Roger</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4238-6fffc78555c8b0ff19fe2da97f37b070ccc02f7b3daaf4daa3f46da3cf8b63973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aging - physiology</topic><topic>Anesthesia</topic><topic>Anesthesia depending on type of surgery</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion - statistics & numerical data</topic><topic>Body Weight - physiology</topic><topic>Cardiopulmonary Bypass - instrumentation</topic><topic>Coronary Artery Bypass</topic><topic>Databases, Factual</topic><topic>Erythrocyte Transfusion</topic><topic>Extracorporeal Circulation - adverse effects</topic><topic>Extracorporeal Circulation - instrumentation</topic><topic>Female</topic><topic>Hematocrit</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Sex Characteristics</topic><topic>Thoracic and cardiovascular surgery. Cardiopulmonary bypass</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scott, Bharathi H.</creatorcontrib><creatorcontrib>Seifert, Frank C.</creatorcontrib><creatorcontrib>Glass, Peter S. A.</creatorcontrib><creatorcontrib>Grimson, Roger</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesia and analgesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scott, Bharathi H.</au><au>Seifert, Frank C.</au><au>Glass, Peter S. A.</au><au>Grimson, Roger</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight</atitle><jtitle>Anesthesia and analgesia</jtitle><addtitle>Anesth Analg</addtitle><date>2003-10-01</date><risdate>2003</risdate><volume>97</volume><issue>4</issue><spage>958</spage><epage>963</epage><pages>958-963</pages><issn>0003-2999</issn><eissn>1526-7598</eissn><coden>AACRAT</coden><abstract><![CDATA[We investigated the impact of cardiopulmonary bypass pump (CPB), hematocrit, gender, age, and body weight on blood use in patients undergoing coronary artery bypass graft surgery at a major university hospital. Participants were 1235 consecutive patients undergoing primary coronary artery surgery over a period of 2 yr (1999 and 2000); 681 patients underwent coronary surgery with use of CPB, and 554 patients underwent off-pump coronary artery bypass surgery using a median sternotomy incision. There were 881 males and 354 females. Average packed red blood cells (PRBC) transfusion for patients on CPB was 3.4 U compared with 1.6 U for the off-pump group (P = <0.001). Patients on CPB received more frequent PRBC transfusion (72.5%) compared with 45.7% of off-pump patients (P = <0.001). Average PRBC transfusion for males was 2.2 U compared with 3.6 U for females (P = <0.001). A lower percentage of males (52.6%) than females (79.4%) received transfusion (P = <0.001). The impact of CPB, off-pump status, preoperative hematocrit <35%, gender, age ≥65 yr, and weight ≤83 kilograms using median values as cut points, on blood use was examined using logistic regression models. Use of CPB, preoperative hematocrit, (<35%) female gender, increasing age, and decreased body weight were significant predictors of transfusion (P = <0.001). Preoperative hematocrit <35% and use of CPB were the strongest predictors of PRBC transfusion.]]></abstract><cop>Hagerstown, MD</cop><pub>International Anesthesia Research Society</pub><pmid>14500140</pmid><doi>10.1213/01.ANE.0000081790.75298.D8</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aging - physiology Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Transfusion - statistics & numerical data Body Weight - physiology Cardiopulmonary Bypass - instrumentation Coronary Artery Bypass Databases, Factual Erythrocyte Transfusion Extracorporeal Circulation - adverse effects Extracorporeal Circulation - instrumentation Female Hematocrit Humans Male Medical sciences Middle Aged Prospective Studies Risk Factors Sex Characteristics Thoracic and cardiovascular surgery. Cardiopulmonary bypass |
| title | Blood Use in Patients Undergoing Coronary Artery Bypass Surgery: Impact Of Cardiopulmonary Bypass Pump, Hematocrit, Gender, Age, and Body Weight |
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