RFP2, c13ORF1, and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia

Occurrence of 13q14 deletions between D13S273 and D13S25 in B-cell chronic lymphocytic leukemia (B-CLL) suggests that the region contains a tumor suppressor gene. We constructed a PAC/cosmid contig largely corresponding to a 380-kb 13q14 YAC insert that we found deleted in a high proportion of B-CLL...

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Veröffentlicht in:	Cancer genetics and cytogenetics 2003-10, Vol.146 (1), p.48-57
Hauptverfasser:	van Everdink, W.J, Baranova, A, Lummen, C, Tyazhelova, T, Looman, M.W.G, Ivanov, D, Verlind, E, Pestova, A, Faber, H, van der Veen, A.Y, Yankovsky, N, Vellenga, E, Buys, C.H.C.M
Format:	Artikel
Sprache:	eng
Schlagworte:	B-Lymphocytes - pathology Chromosome Mapping Chromosomes, Human, Pair 13 DNA Mutational Analysis Expressed Sequence Tags Genes, Tumor Suppressor Humans In Situ Hybridization, Fluorescence Leukemia, Lymphocytic, Chronic, B-Cell - genetics Sequence Deletion
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