Differences in the retinol circulating complex between healthy male and female infants

The concentration of the three components of the retinol circulating complex demonstrates in healthy male infants, but not in females, a transient elevation culminating at 5–6 months after birth. This trimolecular peak is significantly less elevated in bilateral cryptorchid babies. The rise of the r...

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Veröffentlicht in:Clinica chimica acta 1981-08, Vol.114 (2), p.219-224
Hauptverfasser: Ingenbleek, Y., Van den Hove, M.F., Deruelle, M.
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container_title Clinica chimica acta
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creator Ingenbleek, Y.
Van den Hove, M.F.
Deruelle, M.
description The concentration of the three components of the retinol circulating complex demonstrates in healthy male infants, but not in females, a transient elevation culminating at 5–6 months after birth. This trimolecular peak is significantly less elevated in bilateral cryptorchid babies. The rise of the retinol related parameters seems directly induced by the testosterone hypersecretion previously described in male infants at 2–3 months. The delay in the liver response in terms of retinol secretion appears to depend on a temporary functional immaturity and/or a transitory depression of the hepatic protein-synthesizing machinery. The surge of the retinol circulating complex could play a crucial role in the O-mannosylation of several glycoproteins involved in male sexual differentiation.
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subjects Aging
Cryptorchidism - blood
Female
Humans
Infant
Infant, Newborn
Male
Retinol-Binding Proteins - metabolism
Senegal
Sex Factors
Thyroxine-Binding Proteins - metabolism
Vitamin A - blood
title Differences in the retinol circulating complex between healthy male and female infants
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