Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome
Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other a...
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| Veröffentlicht in: | Saudi medical journal 2003-09, Vol.24 (9), p.1013-1015 |
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| creator | SAXENA, Shiv K BIN SALIH, Salih A AL-JIZEERI, Ahmed H KHEIR, Osman A |
| description | Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other autoimmune, infectious or neoplastic disorders. In this paper we report a 29-year-old Saudi female, a known case of antiphospholipid syndrome, presented with complaints of fever, breathlessness and generalized fatigue. Further investigations confirmed her as a case of myeloblastic leukemia (M1, French-American-British classification). Acute myeloblastic leukemia is not described to be associated with primary antiphospholipid syndrome in the literature to date. This is the first case report of such association. |
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Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other autoimmune, infectious or neoplastic disorders. In this paper we report a 29-year-old Saudi female, a known case of antiphospholipid syndrome, presented with complaints of fever, breathlessness and generalized fatigue. Further investigations confirmed her as a case of myeloblastic leukemia (M1, French-American-British classification). Acute myeloblastic leukemia is not described to be associated with primary antiphospholipid syndrome in the literature to date. This is the first case report of such association.</description><identifier>ISSN: 0379-5284</identifier><identifier>PMID: 12973490</identifier><identifier>CODEN: SAMJDI</identifier><language>eng</language><publisher>Riyadh: Saudi Medical Journal</publisher><subject>Adult ; Antiphospholipid Syndrome - complications ; Biological and medical sciences ; Bone Marrow - immunology ; Bone Marrow - pathology ; Dyspnea - diagnosis ; Fatigue - diagnosis ; Fever - diagnosis ; Hematologic and hematopoietic diseases ; Humans ; Immunophenotyping ; Leukemia, Myeloid, Acute - complications ; Leukemia, Myeloid, Acute - immunology ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Male ; Medical sciences ; Platelet diseases and coagulopathies ; Saudi Arabia ; Tropical medicine</subject><ispartof>Saudi medical journal, 2003-09, Vol.24 (9), p.1013-1015</ispartof><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15166282$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12973490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAXENA, Shiv K</creatorcontrib><creatorcontrib>BIN SALIH, Salih A</creatorcontrib><creatorcontrib>AL-JIZEERI, Ahmed H</creatorcontrib><creatorcontrib>KHEIR, Osman A</creatorcontrib><title>Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome</title><title>Saudi medical journal</title><addtitle>Saudi Med J</addtitle><description>Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. Antiphospholipid syndrome may occur as a primary disease or in patients with systemic lupus erythematosus or other autoimmune, infectious or neoplastic disorders. In this paper we report a 29-year-old Saudi female, a known case of antiphospholipid syndrome, presented with complaints of fever, breathlessness and generalized fatigue. Further investigations confirmed her as a case of myeloblastic leukemia (M1, French-American-British classification). Acute myeloblastic leukemia is not described to be associated with primary antiphospholipid syndrome in the literature to date. This is the first case report of such association.</description><subject>Adult</subject><subject>Antiphospholipid Syndrome - complications</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow - immunology</subject><subject>Bone Marrow - pathology</subject><subject>Dyspnea - diagnosis</subject><subject>Fatigue - diagnosis</subject><subject>Fever - diagnosis</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Immunophenotyping</subject><subject>Leukemia, Myeloid, Acute - complications</subject><subject>Leukemia, Myeloid, Acute - immunology</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Platelet diseases and coagulopathies</subject><subject>Saudi Arabia</subject><subject>Tropical medicine</subject><issn>0379-5284</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0MtKxDAUBuAsFGccfQXJRneF5tJclsPgDQZmo-tykiZMNL3YpEjf3oIVF4fDDx8H_nOBtiWTuqio4ht0ndJHWTIhSnGFNoRqybgut-i0t1N2uJ1d7E2ElIPF0U2frg2AQ4cBD5CD6zL-DvmMhzG0MM4YuhyGc5-WiWEIDU5z14x9627QpYeY3O26d-j96fHt8FIcT8-vh_2xGCiTuaDSek-4UF4ra0rKDeXES2OtIkYDASrALAkk141rfKWUB2q4JZbqihi2Qw-_d4ex_5pcynUbknUxQuf6KdWSiUpJJhd4t8LJtK6p1wb13wsWcL8CSBaiH6GzIf27ighBFWU_mHRl8Q</recordid><startdate>20030901</startdate><enddate>20030901</enddate><creator>SAXENA, Shiv K</creator><creator>BIN SALIH, Salih A</creator><creator>AL-JIZEERI, Ahmed H</creator><creator>KHEIR, Osman A</creator><general>Saudi Medical Journal</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20030901</creationdate><title>Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome</title><author>SAXENA, Shiv K ; BIN SALIH, Salih A ; AL-JIZEERI, Ahmed H ; KHEIR, Osman A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p237t-27cff1468f98cb024b241f7bcc81b9a1a26abbcca749dedf588fa2b4c1c2951b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Antiphospholipid Syndrome - complications</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow - immunology</topic><topic>Bone Marrow - pathology</topic><topic>Dyspnea - diagnosis</topic><topic>Fatigue - diagnosis</topic><topic>Fever - diagnosis</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Immunophenotyping</topic><topic>Leukemia, Myeloid, Acute - complications</topic><topic>Leukemia, Myeloid, Acute - immunology</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Platelet diseases and coagulopathies</topic><topic>Saudi Arabia</topic><topic>Tropical medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SAXENA, Shiv K</creatorcontrib><creatorcontrib>BIN SALIH, Salih A</creatorcontrib><creatorcontrib>AL-JIZEERI, Ahmed H</creatorcontrib><creatorcontrib>KHEIR, Osman A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Saudi medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAXENA, Shiv K</au><au>BIN SALIH, Salih A</au><au>AL-JIZEERI, Ahmed H</au><au>KHEIR, Osman A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome</atitle><jtitle>Saudi medical journal</jtitle><addtitle>Saudi Med J</addtitle><date>2003-09-01</date><risdate>2003</risdate><volume>24</volume><issue>9</issue><spage>1013</spage><epage>1015</epage><pages>1013-1015</pages><issn>0379-5284</issn><coden>SAMJDI</coden><abstract>Antiphospholipid syndrome is characterized by venous and arterial thrombosis, recurrent pregnancy loss and the presence of the lupus anticoagulant, anticardiolipin antibodies or both. 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| ispartof | Saudi medical journal, 2003-09, Vol.24 (9), p.1013-1015 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Antiphospholipid Syndrome - complications Biological and medical sciences Bone Marrow - immunology Bone Marrow - pathology Dyspnea - diagnosis Fatigue - diagnosis Fever - diagnosis Hematologic and hematopoietic diseases Humans Immunophenotyping Leukemia, Myeloid, Acute - complications Leukemia, Myeloid, Acute - immunology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Platelet diseases and coagulopathies Saudi Arabia Tropical medicine |
| title | Acute myeloblastic leukemia in a patient with primary antiphospholipid syndrome |
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