Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes

Overweight and obesity are major contributors to both type 2 diabetes and cardiovascular disease (CVD). Moreover, individuals with type 2 diabetes who are overweight or obese are at particularly high risk for CVD morbidity and mortality. Although short-term weight loss has been shown to ameliorate o...

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Veröffentlicht in:	Controlled clinical trials 2003-10, Vol.24 (5), p.610-628
Hauptverfasser:	Ryan, Donna H, Espeland, Mark A, Foster, Gary D, Haffner, Steven M, Hubbard, Van S, Johnson, Karen C, Kahn, Steven E, Knowler, William C, Yanovski, Susan Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Behavioral interventions Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control CVD Diabetes Mellitus, Type 2 - complications Disease prevention Health promotion Humans Lifestyle programs Middle Aged Monitoring, Physiologic Obesity Obesity - complications Patient Education as Topic Patient Selection Physical activity Randomized Controlled Trials as Topic - methods Research Design Risk Reduction Behavior Type 2 diabetes mellitus Weight loss Weight Loss - physiology Weight loss maintenance
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