Selective Pressure-Regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia

We sought to improve regional myocardial delivery and subsequent collateral perfusion induced by basic fibroblast growth factor-2 (FGF-2) using selective pressure-regulated retroinfusion of coronary veins for delivery. This hypothesis was tested in a newly developed pig model with percutaneous induc...

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Veröffentlicht in:	Journal of the American College of Cardiology 2003-09, Vol.42 (6), p.1120-1128
Hauptverfasser:	von Degenfeld, Georges, Raake, Philip, Kupatt, Christian, Lebherz, Corinna, Hinkel, Rabea, Gildehaus, Franz Josef, Münzing, Wolfgang, Kranz, Andrea, Waltenberger, Johannes, Simoes, Marcus, Schwaiger, Markus, Thein, Eckart, Boekstegers, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Cardiology Coronary Circulation - drug effects Coronary Vessels Fibroblast Growth Factor 2 - administration & dosage Heart - drug effects Heart - physiology Heart attacks Hogs Infusions, Intravenous - methods Ischemia Laboratory animals Myocardial Ischemia - physiopathology Pressure Proteins Swine Vascular endothelial growth factor Veins & arteries
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