Induction of Tissue Factor in the Arterial Wall During Recurrent Thrombus Formation

OBJECTIVE—Tissue factor (TF) is normally expressed at low levels in the media of blood vessels, but it is readily induced after vessel injury. It is not known whether vascular damage per se or thrombus formation is responsible for this phenomenon. METHODS AND RESULTS—Cyclic flow variations (CFVs), a...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2003-09, Vol.23 (9), p.1684-1689
Hauptverfasser:	D’Andrea, Davide, Ravera, Marta, Golino, Paolo, Rosica, Annamaria, De Felice, Mario, Ragni, Massimo, Cirillo, Plinio, Vigorito, Francesco, Corcione, Nicola, Tommasini, Paola, Gargiulo, Annarita, Piro, Orlando, Calabró, Paolo, Chiariello, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Platelets - chemistry Blood Platelets - physiology Carotid Arteries - chemistry Carotid Arteries - pathology Carotid Artery Thrombosis - metabolism Carotid Artery Thrombosis - pathology Carotid Stenosis - metabolism Carotid Stenosis - pathology Disease Models, Animal Hematologic and hematopoietic diseases In Situ Hybridization - methods Medical sciences Monocytes - chemistry Monocytes - pathology Muscle, Smooth, Vascular - chemistry Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Neutrophils - chemistry Neutrophils - pathology Platelet Activating Factor - pharmacology Platelet diseases and coagulopathies Platelet-Derived Growth Factor - pharmacology Rabbits Recurrence Regional Blood Flow - physiology RNA, Messenger - biosynthesis Thromboplastin - biosynthesis Thromboplastin - metabolism Tunica Intima - chemistry Tunica Intima - metabolism Tunica Intima - pathology Tunica Media - chemistry Tunica Media - metabolism Tunica Media - pathology
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