Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene

A number of chromosomal abnormalities including 19q deletions have been associated with the formation of human gliomas. In this study, we employed a proteomics-based approach to identify possible genes involved in glioma tumorigenesis which may serve as potential diagnostic molecular markers for thi...

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Veröffentlicht in:	Biochemical and biophysical research communications 2003-09, Vol.309 (3), p.558-566
Hauptverfasser:	Hiratsuka, Masaharu, Inoue, Toshiaki, Toda, Tosifusa, Kimura, Narimichi, Shirayoshi, Yasuaki, Kamitani, Hideki, Watanabe, Takashi, Ohama, Eisaku, Tahimic, Candice G.T, Kurimasa, Akihiro, Oshimura, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	19q13 Blotting, Northern Brain Neoplasms - enzymology Brain Neoplasms - genetics Brain Neoplasms - ultrastructure Cell Division Cytoskeleton Down-Regulation Electrophoresis, Gel, Two-Dimensional Enzyme Repression Gene Expression Regulation, Neoplastic Glioma Glioma - enzymology Glioma - genetics Glioma - ultrastructure Growth inhibition Humans Microtubules - ultrastructure Neoplasm Proteins - analysis Proteomics SIRT2 Sirtuin 2 Sirtuins - genetics Sirtuins - metabolism Tumor Cells, Cultured
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