Locally delivered minocycline microspheres for the treatment of periodontitis in smokers

Aim: The aim of the present analysis of a larger phase 3 clinical trial was to evaluate the efficacy of 1 mg minocycline hydrochloride microencapsulated in 3 mg of resorbable polymer, subgingivally administered as an adjunct to scaling and root planing (SRP) in smokers with chronic periodontitis. Ma...

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Veröffentlicht in:	Journal of clinical periodontology 2003-09, Vol.30 (9), p.787-794
Hauptverfasser:	Paquette, David, Oringer, Richard, Lessem, Jan, Offenbacher, Steven, Genco, Robert, Persson, G. Rutger, Santucci, Edward A., Williams, Ray C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adult Anti-Bacterial Agents - administration & dosage clinical trial Cohort Studies Combined Modality Therapy Dental Scaling Dentistry Female Follow-Up Studies Humans Male Microspheres Middle Aged Minocycline - administration & dosage minocycline/therapeutic use Periodontal Pocket - drug therapy Periodontal Pocket - therapy Periodontitis - drug therapy Periodontitis - therapy Pharmaceutical Vehicles Root Planing Single-Blind Method Smoking Wound Healing
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