Management of sickle hemoglobinopathies in pregnant patients
During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. P...
Gespeichert in:
| Veröffentlicht in: | American journal of obstetrics and gynecology 1981-10, Vol.141 (3), p.237-241 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 241 |
|---|---|
| container_issue | 3 |
| container_start_page | 237 |
| container_title | American journal of obstetrics and gynecology |
| container_volume | 141 |
| creator | Miller, Joseph M. Horger, Edgar O. Key, Thomas C. Walker, Ernest M. |
| description | During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. Prophylactic exchange transfusion was not associated with improved pregnancy outcome and was associated with significant antibody formation. Exchange transfusion may best be reserved as a treatment modality when infection, crisis, or symptomatic anemia occurs in patients with a sickle hemoglobinopathy. |
| doi_str_mv | 10.1016/S0002-9378(16)32625-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73647566</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002937816326254</els_id><sourcerecordid>73647566</sourcerecordid><originalsourceid>FETCH-LOGICAL-c360t-3fc0f8929ff05a1c1caea177bd828d1798c5305aa37a1aaf75ea5a725b511ff43</originalsourceid><addsrcrecordid>eNqFkF9LwzAUxYMoc04_wqBPog_VJF2SFgSR4T-Y-KA-hzS92aJtU5NO8NubbmOvPoWbc-499_4QmhJ8RTDh128YY5oWmcgvCL_MKKcsnR2gMcGFSHnO80M03luO0UkIn0NJCzpCI0FzmuPZGN28qFYtoYG2T5xJgtVfNSQraNyydqVtXaf6lYWQ2DbpPCxbFY3xz8aGcIqOjKoDnO3eCfp4uH-fP6WL18fn-d0i1RnHfZoZjU1e0MIYzBTRRCtQRIiyiktURBS5ZllUVCYUUcoIBoopQVnJCDFmlk3Q-XZu5933GkIvGxs01LVqwa2DFBmfCcZ5NLKtUXsXggcjO28b5X8lwXKgJjfU5IBExmpDTQ4B013Aumyg2nftMEX9dqtDvPLHgpdBRwIaKutB97Jy9p-EPxKhfKc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73647566</pqid></control><display><type>article</type><title>Management of sickle hemoglobinopathies in pregnant patients</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Miller, Joseph M. ; Horger, Edgar O. ; Key, Thomas C. ; Walker, Ernest M.</creator><creatorcontrib>Miller, Joseph M. ; Horger, Edgar O. ; Key, Thomas C. ; Walker, Ernest M.</creatorcontrib><description>During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. Prophylactic exchange transfusion was not associated with improved pregnancy outcome and was associated with significant antibody formation. Exchange transfusion may best be reserved as a treatment modality when infection, crisis, or symptomatic anemia occurs in patients with a sickle hemoglobinopathy.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/S0002-9378(16)32625-4</identifier><identifier>PMID: 7282804</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anemia, Sickle Cell - complications ; Anemia, Sickle Cell - therapy ; Exchange Transfusion, Whole Blood ; Female ; Fetal Monitoring ; Humans ; Infant, Newborn ; Isoantibodies - biosynthesis ; Pregnancy ; Pregnancy Complications, Hematologic - therapy ; Prenatal Care ; Risk</subject><ispartof>American journal of obstetrics and gynecology, 1981-10, Vol.141 (3), p.237-241</ispartof><rights>1981 The C. V. Mosby Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-3fc0f8929ff05a1c1caea177bd828d1798c5305aa37a1aaf75ea5a725b511ff43</citedby><cites>FETCH-LOGICAL-c360t-3fc0f8929ff05a1c1caea177bd828d1798c5305aa37a1aaf75ea5a725b511ff43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0002-9378(16)32625-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7282804$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Miller, Joseph M.</creatorcontrib><creatorcontrib>Horger, Edgar O.</creatorcontrib><creatorcontrib>Key, Thomas C.</creatorcontrib><creatorcontrib>Walker, Ernest M.</creatorcontrib><title>Management of sickle hemoglobinopathies in pregnant patients</title><title>American journal of obstetrics and gynecology</title><addtitle>Am J Obstet Gynecol</addtitle><description>During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. Prophylactic exchange transfusion was not associated with improved pregnancy outcome and was associated with significant antibody formation. Exchange transfusion may best be reserved as a treatment modality when infection, crisis, or symptomatic anemia occurs in patients with a sickle hemoglobinopathy.</description><subject>Anemia, Sickle Cell - complications</subject><subject>Anemia, Sickle Cell - therapy</subject><subject>Exchange Transfusion, Whole Blood</subject><subject>Female</subject><subject>Fetal Monitoring</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Isoantibodies - biosynthesis</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Hematologic - therapy</subject><subject>Prenatal Care</subject><subject>Risk</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF9LwzAUxYMoc04_wqBPog_VJF2SFgSR4T-Y-KA-hzS92aJtU5NO8NubbmOvPoWbc-499_4QmhJ8RTDh128YY5oWmcgvCL_MKKcsnR2gMcGFSHnO80M03luO0UkIn0NJCzpCI0FzmuPZGN28qFYtoYG2T5xJgtVfNSQraNyydqVtXaf6lYWQ2DbpPCxbFY3xz8aGcIqOjKoDnO3eCfp4uH-fP6WL18fn-d0i1RnHfZoZjU1e0MIYzBTRRCtQRIiyiktURBS5ZllUVCYUUcoIBoopQVnJCDFmlk3Q-XZu5933GkIvGxs01LVqwa2DFBmfCcZ5NLKtUXsXggcjO28b5X8lwXKgJjfU5IBExmpDTQ4B013Aumyg2nftMEX9dqtDvPLHgpdBRwIaKutB97Jy9p-EPxKhfKc</recordid><startdate>19811001</startdate><enddate>19811001</enddate><creator>Miller, Joseph M.</creator><creator>Horger, Edgar O.</creator><creator>Key, Thomas C.</creator><creator>Walker, Ernest M.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19811001</creationdate><title>Management of sickle hemoglobinopathies in pregnant patients</title><author>Miller, Joseph M. ; Horger, Edgar O. ; Key, Thomas C. ; Walker, Ernest M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-3fc0f8929ff05a1c1caea177bd828d1798c5305aa37a1aaf75ea5a725b511ff43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Anemia, Sickle Cell - complications</topic><topic>Anemia, Sickle Cell - therapy</topic><topic>Exchange Transfusion, Whole Blood</topic><topic>Female</topic><topic>Fetal Monitoring</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Isoantibodies - biosynthesis</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Hematologic - therapy</topic><topic>Prenatal Care</topic><topic>Risk</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miller, Joseph M.</creatorcontrib><creatorcontrib>Horger, Edgar O.</creatorcontrib><creatorcontrib>Key, Thomas C.</creatorcontrib><creatorcontrib>Walker, Ernest M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miller, Joseph M.</au><au>Horger, Edgar O.</au><au>Key, Thomas C.</au><au>Walker, Ernest M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Management of sickle hemoglobinopathies in pregnant patients</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1981-10-01</date><risdate>1981</risdate><volume>141</volume><issue>3</issue><spage>237</spage><epage>241</epage><pages>237-241</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>During the past decade, pregnancy outcome has improved among patients with sickle hemoglobinopathies. The role of prophylactic exchange transfusion in this improvement is uncertain. This study reviews the experience in 64 pregnancies managed at the Medical University Hospital over a 7 year period. Prophylactic exchange transfusion was not associated with improved pregnancy outcome and was associated with significant antibody formation. Exchange transfusion may best be reserved as a treatment modality when infection, crisis, or symptomatic anemia occurs in patients with a sickle hemoglobinopathy.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7282804</pmid><doi>10.1016/S0002-9378(16)32625-4</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9378 |
| ispartof | American journal of obstetrics and gynecology, 1981-10, Vol.141 (3), p.237-241 |
| issn | 0002-9378 1097-6868 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73647566 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anemia, Sickle Cell - complications Anemia, Sickle Cell - therapy Exchange Transfusion, Whole Blood Female Fetal Monitoring Humans Infant, Newborn Isoantibodies - biosynthesis Pregnancy Pregnancy Complications, Hematologic - therapy Prenatal Care Risk |
| title | Management of sickle hemoglobinopathies in pregnant patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T21%3A04%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Management%20of%20sickle%20hemoglobinopathies%20in%20pregnant%20patients&rft.jtitle=American%20journal%20of%20obstetrics%20and%20gynecology&rft.au=Miller,%20Joseph%20M.&rft.date=1981-10-01&rft.volume=141&rft.issue=3&rft.spage=237&rft.epage=241&rft.pages=237-241&rft.issn=0002-9378&rft.eissn=1097-6868&rft_id=info:doi/10.1016/S0002-9378(16)32625-4&rft_dat=%3Cproquest_cross%3E73647566%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73647566&rft_id=info:pmid/7282804&rft_els_id=S0002937816326254&rfr_iscdi=true |