Systemic endotoxaemia following obstructive jaundice: the role of lactulose

Obstructive jaundice is often accompanied by bacterial translocation and subsequent sepsis. The effect of lactulose in preventing that process was evaluated in an experimental model. Obstructive jaundice was induced in 23 rabbits after common bile duct ligation. Animals were divided into two groups....

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Veröffentlicht in:	The Journal of surgical research 2003-08, Vol.113 (2), p.243-247
Hauptverfasser:	Koutelidakis, Ioannis, Papaziogas, Basilios, Giamarellos-Bourboulis, Evangelos J, Makris, John, Pavlidis, Theodoros, Giamarellou, Helen, Papaziogas, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Bacterial Translocation - drug effects Biological and medical sciences Cholangitis - etiology Cholestasis - etiology Common Bile Duct - surgery Digestive system endotoxaemia Endotoxemia - etiology Endotoxemia - prevention & control Gastrointestinal Agents - pharmacology lactulose Lactulose - pharmacology Ligation - adverse effects Lipopolysaccharides - blood Male Malondialdehyde - blood Medical sciences Models, Animal obstructive jaundice Pharmacology. Drug treatments Rabbits systemic inflammatory response Systemic Inflammatory Response Syndrome - etiology Systemic Inflammatory Response Syndrome - prevention & control Tumor Necrosis Factor-alpha - analysis
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