A ‘receptor’ for protons in small neurons of trigeminal ganglia: Possible role in nociception
Neurons of the rat's trigeminal ganglion were enzymatically isolated and investigated under the conditions of intracellular perfusion and voltage clamp. Recently discovered proton-activated sodium conductance was found in about half of the neurons. The majority of these proton-sensitive neurons...
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| Veröffentlicht in: | Neuroscience letters 1981-07, Vol.24 (3), p.243-246 |
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| container_end_page | 246 |
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| container_title | Neuroscience letters |
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| creator | Krishtal, O.A. Pidoplichko, V.I. |
| description | Neurons of the rat's trigeminal ganglion were enzymatically isolated and investigated under the conditions of intracellular perfusion and voltage clamp. Recently discovered proton-activated sodium conductance was found in about half of the neurons. The majority of these proton-sensitive neurons (74%) were less than 26 μm in diameter, whereas most of the proton-insensitive cells (75%) were larger than 26 μm in diameter. The possibility is discussed that the small proton-sensitive neurons may participate in nociception. |
| doi_str_mv | 10.1016/0304-3940(81)90164-6 |
| format | Article |
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The possibility is discussed that the small proton-sensitive neurons may participate in nociception.</description><subject>Animals</subject><subject>ganglia</subject><subject>Hydrogen-Ion Concentration</subject><subject>Kinetics</subject><subject>neurons</subject><subject>Neurons - physiology</subject><subject>Nociceptors - physiology</subject><subject>pain</subject><subject>Protons</subject><subject>Rats</subject><subject>Sodium - metabolism</subject><subject>Trigeminal Ganglion - physiology</subject><subject>Trigeminal Nerve - physiology</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUcFqGzEQFSXBcd3-QQM6heawibTSSqscAsa0TcGQHNqzkLWzRmFXcqR1oDd_Rvp7_pJoa5NjepmBmffeSO8h9IWSK0qouCaM8IIpTr7W9FLlCS_EBzSltSwLqWR5gqZvkDP0MaVHQkhFKz5BE1EKRUoxRWaO97uXCBY2Q4j73V_chog3MQzBJ-w8Tr3pOuxhG8dBaPEQ3Rp6502H18avO2du8ENIya06wDHkklk-WDdKuuA_odPWdAk-H_sM_f7-7dfirlje__i5mC8Lyys-FLJhreKGcaaUrXlLlRGcK8mYbIWo5YqDYlKWVvFVU4ExTJqqqhllJa2hrdgMXRx08-OftpAG3btkoeuMh7BNWjLBBZflf4G0KhWrs_QM8QPQxvy_CK3eRNeb-EdToscI9OivHv3VNdX_ItAi086P-ttVD80b6eh53t8e9pDdeHYQdbIOvIXG5RwG3QT3_oFXGwyWgQ</recordid><startdate>19810717</startdate><enddate>19810717</enddate><creator>Krishtal, O.A.</creator><creator>Pidoplichko, V.I.</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19810717</creationdate><title>A ‘receptor’ for protons in small neurons of trigeminal ganglia: Possible role in nociception</title><author>Krishtal, O.A. ; Pidoplichko, V.I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-7d3f94a34399c84f19a64497337f6687b4e93772c94bd5eaa37a558313218ef53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Animals</topic><topic>ganglia</topic><topic>Hydrogen-Ion Concentration</topic><topic>Kinetics</topic><topic>neurons</topic><topic>Neurons - physiology</topic><topic>Nociceptors - physiology</topic><topic>pain</topic><topic>Protons</topic><topic>Rats</topic><topic>Sodium - metabolism</topic><topic>Trigeminal Ganglion - physiology</topic><topic>Trigeminal Nerve - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krishtal, O.A.</creatorcontrib><creatorcontrib>Pidoplichko, V.I.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krishtal, O.A.</au><au>Pidoplichko, V.I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A ‘receptor’ for protons in small neurons of trigeminal ganglia: Possible role in nociception</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1981-07-17</date><risdate>1981</risdate><volume>24</volume><issue>3</issue><spage>243</spage><epage>246</epage><pages>243-246</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><abstract>Neurons of the rat's trigeminal ganglion were enzymatically isolated and investigated under the conditions of intracellular perfusion and voltage clamp. 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| fulltext | fulltext |
| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1981-07, Vol.24 (3), p.243-246 |
| issn | 0304-3940 1872-7972 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_73646472 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals ganglia Hydrogen-Ion Concentration Kinetics neurons Neurons - physiology Nociceptors - physiology pain Protons Rats Sodium - metabolism Trigeminal Ganglion - physiology Trigeminal Nerve - physiology |
| title | A ‘receptor’ for protons in small neurons of trigeminal ganglia: Possible role in nociception |
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