Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population

To determine the mechanism by which cotransplantation of a donor kidney and heart allograft induces tolerance to both organs in miniature swine, we examined the renal elements responsible for tolerance induction. Recipients received 12 days of cyclosporine, and transplants were performed across a ma...

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Veröffentlicht in:	Transplantation 2003-08, Vol.76 (4), p.625-631
Hauptverfasser:	Mezrich, Joshua D, Yamada, Kazuhiko, Lee, Richard S, Mawulawde, Kwabena, Benjamin, Louis C, Schwarze, Margaret L, Maloney, Michaella E, Amoah, Hannah C, Houser, Stuart L, Sachs, David H, Madsen, Joren C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Heart - radiation effects Heart Transplantation - adverse effects Heart Transplantation - immunology Kidney - cytology Kidney - radiation effects Kidney Transplantation - immunology Leukapheresis Radiation Tolerance Swine Swine, Miniature Transplantation Tolerance Transplantation, Homologous
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