Drug resistance and the microenvironment: nature and nurture

Drug resistance remains a major obstacle to the successful use of chemotherapeutic drugs for cancer therapy. It is well documented that cancer cells can adapt to the presence of chemotherapeutic agents through mutations or expression changes of key genes that control drug metabolism or response to d...

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Veröffentlicht in:	Drug resistance updates 2003-08, Vol.6 (4), p.169-172
1. Verfasser:	Morin, Patrice J
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - physiology Cell Adhesion - drug effects Cell Adhesion - physiology Chemoresistance Cisplatin Collagen IV Collagen VI Drug Resistance, Neoplasm - physiology Extracellular matrix Extracellular Matrix - drug effects Extracellular Matrix - physiology Humans Models, Biological
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