Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections
The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure. Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) under...
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description | The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure.
Retrospective study.
Cardiothoracic surgery unit.
Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months).
The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p < 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p < 0.001 [postoperatively vs preoperatively]).
In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation. |
doi_str_mv | 10.1378/chest.124.3.984 |
format | Article |
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Retrospective study.
Cardiothoracic surgery unit.
Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months).
The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p < 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p < 0.001 [postoperatively vs preoperatively]).
In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.124.3.984</identifier><identifier>PMID: 12970027</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Actuarial Analysis ; Adult ; Aged ; Aneurysm, Dissecting - diagnostic imaging ; Aneurysm, Dissecting - mortality ; Aneurysm, Dissecting - surgery ; aortic aneurysm ; Aortic Aneurysm, Thoracic - diagnostic imaging ; Aortic Aneurysm, Thoracic - mortality ; Aortic Aneurysm, Thoracic - surgery ; aortic root replacement ; Bentall technique ; Biological and medical sciences ; Blood Vessel Prosthesis ; composite graft ; Coronary Vessels - surgery ; dissecting aneurysm ; Echocardiography ; Female ; Follow-Up Studies ; Heart Valve Prosthesis ; Humans ; Italy ; Male ; Medical sciences ; Middle Aged ; Prosthesis Design ; Retrospective Studies ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Survival Rate ; Treatment Outcome ; Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</subject><ispartof>Chest, 2003-09, Vol.124 (3), p.984-988</ispartof><rights>2003 The American College of Chest Physicians</rights><rights>2004 INIST-CNRS</rights><rights>Copyright American College of Chest Physicians Sep 2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-49e1d6a742ea0ddafa9c0dc9421d99ac5b6175d05e83d327f84ac1b1669d3de23</citedby><cites>FETCH-LOGICAL-c440t-49e1d6a742ea0ddafa9c0dc9421d99ac5b6175d05e83d327f84ac1b1669d3de23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15114480$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12970027$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gelsomino, Sandro</creatorcontrib><creatorcontrib>Morocutti, Giorgio</creatorcontrib><creatorcontrib>Frassani, Romeo</creatorcontrib><creatorcontrib>Masullo, Gianluca</creatorcontrib><creatorcontrib>Da Col, Paolo</creatorcontrib><creatorcontrib>Spedicato, Leonardo</creatorcontrib><creatorcontrib>Livi, Ugolino</creatorcontrib><title>Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections</title><title>Chest</title><addtitle>Chest</addtitle><description>The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure.
Retrospective study.
Cardiothoracic surgery unit.
Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months).
The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p < 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p < 0.001 [postoperatively vs preoperatively]).
In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</description><subject>Actuarial Analysis</subject><subject>Adult</subject><subject>Aged</subject><subject>Aneurysm, Dissecting - diagnostic imaging</subject><subject>Aneurysm, Dissecting - mortality</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>aortic aneurysm</subject><subject>Aortic Aneurysm, Thoracic - diagnostic imaging</subject><subject>Aortic Aneurysm, Thoracic - mortality</subject><subject>Aortic Aneurysm, Thoracic - surgery</subject><subject>aortic root replacement</subject><subject>Bentall technique</subject><subject>Biological and medical sciences</subject><subject>Blood Vessel Prosthesis</subject><subject>composite graft</subject><subject>Coronary Vessels - surgery</subject><subject>dissecting aneurysm</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart Valve Prosthesis</subject><subject>Humans</subject><subject>Italy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prosthesis Design</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><subject>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kc2LEzEYxoMobl09e5MguLfp5msmzbFb1w8oCIueQ5q802aZSWqSUfa_N2tHKoKnEPg9H7wPQq8pWVIuV9f2ALksKRNLvlQr8QQtqOK04a3gT9GCEMoa3il2gV7kfE_qn6ruObqgTElCmFygcRvDvimQRnwHeRpKxrHHNxCKGQa8ieMxZl8Ar2Mq3uK7GEsFj4OxMFYI9zHhdbYQnA_7P9Q6wJQe8pixCQ6_9zmDLT6G_BI9682Q4dX8XqJvH26_bj412y8fP2_W28YKQUojFFDXGSkYGOKc6Y2yxFklGHVKGdvuOipbR1pYcceZ7FfCWLqjXaccd8D4Jbo6-R5T_D7VE-nR15LDYALEKWvJO94RqSr49h_wPk4p1G6aESKUlN0jdH2CbIo5J-j1MfnRpAdNiX6cQf-eQdcZNNd1hqp4M9tOuxHcmZ_vXoF3M2CyNUOfTLA-n7mWUiFW5Bx98PvDT59A57EOU235KXSu-3e0Oimg3veHh6Sz9RAsuKq2Rbvo_1v7F9-Utq4</recordid><startdate>20030901</startdate><enddate>20030901</enddate><creator>Gelsomino, Sandro</creator><creator>Morocutti, Giorgio</creator><creator>Frassani, Romeo</creator><creator>Masullo, Gianluca</creator><creator>Da Col, Paolo</creator><creator>Spedicato, Leonardo</creator><creator>Livi, Ugolino</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20030901</creationdate><title>Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections</title><author>Gelsomino, Sandro ; Morocutti, Giorgio ; Frassani, Romeo ; Masullo, Gianluca ; Da Col, Paolo ; Spedicato, Leonardo ; Livi, Ugolino</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-49e1d6a742ea0ddafa9c0dc9421d99ac5b6175d05e83d327f84ac1b1669d3de23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Actuarial Analysis</topic><topic>Adult</topic><topic>Aged</topic><topic>Aneurysm, Dissecting - diagnostic imaging</topic><topic>Aneurysm, Dissecting - mortality</topic><topic>Aneurysm, Dissecting - surgery</topic><topic>aortic aneurysm</topic><topic>Aortic Aneurysm, Thoracic - diagnostic imaging</topic><topic>Aortic Aneurysm, Thoracic - mortality</topic><topic>Aortic Aneurysm, Thoracic - surgery</topic><topic>aortic root replacement</topic><topic>Bentall technique</topic><topic>Biological and medical sciences</topic><topic>Blood Vessel Prosthesis</topic><topic>composite graft</topic><topic>Coronary Vessels - surgery</topic><topic>dissecting aneurysm</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart Valve Prosthesis</topic><topic>Humans</topic><topic>Italy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prosthesis Design</topic><topic>Retrospective Studies</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Survival Rate</topic><topic>Treatment Outcome</topic><topic>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gelsomino, Sandro</creatorcontrib><creatorcontrib>Morocutti, Giorgio</creatorcontrib><creatorcontrib>Frassani, Romeo</creatorcontrib><creatorcontrib>Masullo, Gianluca</creatorcontrib><creatorcontrib>Da Col, Paolo</creatorcontrib><creatorcontrib>Spedicato, Leonardo</creatorcontrib><creatorcontrib>Livi, Ugolino</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gelsomino, Sandro</au><au>Morocutti, Giorgio</au><au>Frassani, Romeo</au><au>Masullo, Gianluca</au><au>Da Col, Paolo</au><au>Spedicato, Leonardo</au><au>Livi, Ugolino</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2003-09-01</date><risdate>2003</risdate><volume>124</volume><issue>3</issue><spage>984</spage><epage>988</epage><pages>984-988</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure.
Retrospective study.
Cardiothoracic surgery unit.
Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months).
The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p < 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p < 0.001 [postoperatively vs preoperatively]).
In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>12970027</pmid><doi>10.1378/chest.124.3.984</doi><tpages>5</tpages></addata></record> |
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subjects | Actuarial Analysis Adult Aged Aneurysm, Dissecting - diagnostic imaging Aneurysm, Dissecting - mortality Aneurysm, Dissecting - surgery aortic aneurysm Aortic Aneurysm, Thoracic - diagnostic imaging Aortic Aneurysm, Thoracic - mortality Aortic Aneurysm, Thoracic - surgery aortic root replacement Bentall technique Biological and medical sciences Blood Vessel Prosthesis composite graft Coronary Vessels - surgery dissecting aneurysm Echocardiography Female Follow-Up Studies Heart Valve Prosthesis Humans Italy Male Medical sciences Middle Aged Prosthesis Design Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Survival Rate Treatment Outcome Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels |
title | Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections |
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