Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections

The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure. Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) under...

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Veröffentlicht in:Chest 2003-09, Vol.124 (3), p.984-988
Hauptverfasser: Gelsomino, Sandro, Morocutti, Giorgio, Frassani, Romeo, Masullo, Gianluca, Da Col, Paolo, Spedicato, Leonardo, Livi, Ugolino
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container_end_page 988
container_issue 3
container_start_page 984
container_title Chest
container_volume 124
creator Gelsomino, Sandro
Morocutti, Giorgio
Frassani, Romeo
Masullo, Gianluca
Da Col, Paolo
Spedicato, Leonardo
Livi, Ugolino
description The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure. Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months). The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p < 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p < 0.001 [postoperatively vs preoperatively]). In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.
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Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months). The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p &lt; 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p &lt; 0.001 [postoperatively vs preoperatively]). In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.124.3.984</identifier><identifier>PMID: 12970027</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Actuarial Analysis ; Adult ; Aged ; Aneurysm, Dissecting - diagnostic imaging ; Aneurysm, Dissecting - mortality ; Aneurysm, Dissecting - surgery ; aortic aneurysm ; Aortic Aneurysm, Thoracic - diagnostic imaging ; Aortic Aneurysm, Thoracic - mortality ; Aortic Aneurysm, Thoracic - surgery ; aortic root replacement ; Bentall technique ; Biological and medical sciences ; Blood Vessel Prosthesis ; composite graft ; Coronary Vessels - surgery ; dissecting aneurysm ; Echocardiography ; Female ; Follow-Up Studies ; Heart Valve Prosthesis ; Humans ; Italy ; Male ; Medical sciences ; Middle Aged ; Prosthesis Design ; Retrospective Studies ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Survival Rate ; Treatment Outcome ; Vascular surgery: aorta, extremities, vena cava. 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Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months). The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p &lt; 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p &lt; 0.001 [postoperatively vs preoperatively]). In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</description><subject>Actuarial Analysis</subject><subject>Adult</subject><subject>Aged</subject><subject>Aneurysm, Dissecting - diagnostic imaging</subject><subject>Aneurysm, Dissecting - mortality</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>aortic aneurysm</subject><subject>Aortic Aneurysm, Thoracic - diagnostic imaging</subject><subject>Aortic Aneurysm, Thoracic - mortality</subject><subject>Aortic Aneurysm, Thoracic - surgery</subject><subject>aortic root replacement</subject><subject>Bentall technique</subject><subject>Biological and medical sciences</subject><subject>Blood Vessel Prosthesis</subject><subject>composite graft</subject><subject>Coronary Vessels - surgery</subject><subject>dissecting aneurysm</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart Valve Prosthesis</subject><subject>Humans</subject><subject>Italy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prosthesis Design</subject><subject>Retrospective Studies</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Survival Rate</subject><subject>Treatment Outcome</subject><subject>Vascular surgery: aorta, extremities, vena cava. 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Retrospective study. Cardiothoracic surgery unit. Between January 1986 and January 2002, 72 patients (mean age 58.3 ± 12.4 years, 81.9% males) underwent ARR by means of a Bentall operation. Annuloaortic ectasia was the most frequent cause of aortic disease in this series of patients (31 patients; 43.1%), followed by type A dissection (19 patients; 26.3%), atherosclerotic aneurysm (18 patients; 25.1%), and poststenotic dilatation (4 patients; 5.5%). Nine patients (12.5%) had Marfan syndrome, and 10 patients (13.8%) underwent a concomitant replacement of the aortic arch. Follow-up ranged from 2 to 192 months (mean [± SD], 86.6 ± 23.8 months). The mean 30-day mortality rate was 5.5 ± 2%. The mean early mortality rate was 21 ± 4% and 0% (p &lt; 0.001), respectively, in patients with and without dissecting aortic aneurysms. There were two late deaths that were due to a pulmonary neoplasm and a cerebrovascular accident. The mean 16-year survival rate was 91.7 ± 3.2%. The mean hazard of freedom from death was constant beyond 3 years (8.5 ± 3.5%). No patient required reoperation. Furthermore, the long-term clinical follow-up was marked by a complete absence of endocarditis, anticoagulant-related hemorrhage, valve thrombosis, and prosthesis failure. Finally, patients showed a significant improvement in mean New York Heart Association functional status (1.3 ± 0.1; p &lt; 0.001 [postoperatively vs preoperatively]). In our experience, the late results of the Bentall operation were satisfactory. Our findings confirm that this technique still represents the procedure of choice for ARR with coronary reimplantation.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>12970027</pmid><doi>10.1378/chest.124.3.984</doi><tpages>5</tpages></addata></record>
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subjects Actuarial Analysis
Adult
Aged
Aneurysm, Dissecting - diagnostic imaging
Aneurysm, Dissecting - mortality
Aneurysm, Dissecting - surgery
aortic aneurysm
Aortic Aneurysm, Thoracic - diagnostic imaging
Aortic Aneurysm, Thoracic - mortality
Aortic Aneurysm, Thoracic - surgery
aortic root replacement
Bentall technique
Biological and medical sciences
Blood Vessel Prosthesis
composite graft
Coronary Vessels - surgery
dissecting aneurysm
Echocardiography
Female
Follow-Up Studies
Heart Valve Prosthesis
Humans
Italy
Male
Medical sciences
Middle Aged
Prosthesis Design
Retrospective Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Survival Rate
Treatment Outcome
Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels
title Long-term Results of Bentall Composite Aortic Root Replacement for Ascending Aortic Aneurysms and Dissections
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