Characterization of Structural Properties for Morphological Differentiation of Melanosomes: I. Purification of Tyrosinase by Tyrosine Affinity Chromatography and its Characterization in B16 and Harding Passey Melanomas

To characterize how structural properties are related to the morphological differentiation of melanosomes, two forms of melanosomes, commonly seen in mammals, were isolated from B16 and Harding Passey (HP) mouse melanomas. From these morphologically different melanosomes, tyrosinase was solubilized...

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Veröffentlicht in:	Journal of investigative dermatology 1981-08, Vol.77 (2), p.213-218
Hauptverfasser:	Jimbow, Kowichi, Jimbow, Mihoko, Chiba, Masahito
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Catechol Oxidase - analysis Chromatography, Affinity - methods Melanocytes - anatomy & histology Melanocytes - enzymology melanoma Melanoma - enzymology Mice Mice, Inbred BALB C Mice, Inbred C57BL Monophenol Monooxygenase - analysis Neoplasms, Experimental - enzymology purification Skin Neoplasms - enzymology tyrosinase
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