Dendritic cells in peripheral tolerance and immunity
Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the...
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Veröffentlicht in: | APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2003-07, Vol.111 (7-8), p.766-775 |
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container_title | APMIS : acta pathologica, microbiologica et immunologica Scandinavica |
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creator | GAD, MONIKA CLAESSON, MOGENS HELWEG PEDERSEN, ANDERS ELM |
description | Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted. |
doi_str_mv | 10.1034/j.1600-0463.2003.11107808.x |
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language | eng |
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source | Wiley-Blackwell Journals; MEDLINE |
subjects | Animals CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Humans Immune Tolerance - immunology immunity Immunity, Cellular - immunology Lymphocyte Subsets Mice regulatory T cells tolerance toll-like receptors |
title | Dendritic cells in peripheral tolerance and immunity |
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