Dendritic cells in peripheral tolerance and immunity

Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the...

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Veröffentlicht in:APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2003-07, Vol.111 (7-8), p.766-775
Hauptverfasser: GAD, MONIKA, CLAESSON, MOGENS HELWEG, PEDERSEN, ANDERS ELM
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container_title APMIS : acta pathologica, microbiologica et immunologica Scandinavica
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creator GAD, MONIKA
CLAESSON, MOGENS HELWEG
PEDERSEN, ANDERS ELM
description Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.
doi_str_mv 10.1034/j.1600-0463.2003.11107808.x
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source Wiley-Blackwell Journals; MEDLINE
subjects Animals
CD4-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - immunology
Dendritic cells
Dendritic Cells - cytology
Dendritic Cells - immunology
Humans
Immune Tolerance - immunology
immunity
Immunity, Cellular - immunology
Lymphocyte Subsets
Mice
regulatory T cells
tolerance
toll-like receptors
title Dendritic cells in peripheral tolerance and immunity
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