Dendritic cells in peripheral tolerance and immunity

Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2003-07, Vol.111 (7-8), p.766-775
Hauptverfasser:	GAD, MONIKA, CLAESSON, MOGENS HELWEG, PEDERSEN, ANDERS ELM
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Humans Immune Tolerance - immunology immunity Immunity, Cellular - immunology Lymphocyte Subsets Mice regulatory T cells tolerance toll-like receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell‐tolerizing and T cell‐immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.
ISSN:	0903-4641 1600-0463
DOI:	10.1034/j.1600-0463.2003.11107808.x