Protein fouling in microfiltration: deposition mechanism as a function of pressure for different pH

The influence of applied pressure on the fouling mechanism during bovine serum albumin (BSA) dead-end microfiltration (MF) has been investigated for a polyethersulfone acidic negatively charged membrane (ICE-450) from Pall Co. BSA solutions at pH values of 4, 5 (almost equal to the protein isoelectr...

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Veröffentlicht in:Journal of colloid and interface science 2003-10, Vol.266 (1), p.148-152
Hauptverfasser: Velasco, C, Ouammou, M, Calvo, J.I, Hernández, A
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container_title Journal of colloid and interface science
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creator Velasco, C
Ouammou, M
Calvo, J.I
Hernández, A
description The influence of applied pressure on the fouling mechanism during bovine serum albumin (BSA) dead-end microfiltration (MF) has been investigated for a polyethersulfone acidic negatively charged membrane (ICE-450) from Pall Co. BSA solutions at pH values of 4, 5 (almost equal to the protein isoelectric point, IEP), and 6 were microfiltered through the membrane at different applied transmembrane pressures. Results have been analyzed in terms of the usual blocking filtration laws and a substantial change in the fouling mechanism was observed as the pressure was increased, this change can be related to the specific membrane–protein and protein–protein interactions.
doi_str_mv 10.1016/S0021-9797(03)00613-1
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adsorption
Animals
Blocking models
Cattle
Charged membranes
Chemistry
Colloidal state and disperse state
Exact sciences and technology
General and physical chemistry
Hydrogen-Ion Concentration
Membranes
Membranes, Artificial
Microfiltration
Porosity
Pressure
Protein fouling
Protein–membrane interactions
Serum Albumin, Bovine - chemistry
Ultrafiltration - methods
title Protein fouling in microfiltration: deposition mechanism as a function of pressure for different pH
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