Calmodulin activates the isolated catalytic unit of brain adenylate cyclase

The catalytic and guanine nucleotide regulatory (G/F) units of solubilized bovine brain adenylate cyclase were separated by gel filtration as described by Strittmatter, S., and Neer, E. J. ((1980) Proc. Natl. Acad. Sci. U. S. A. 77, 6344-6348). The isolated catalytic unit is activated 4 +/- 1-fold (...

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Veröffentlicht in:	The Journal of biological chemistry 1981-10, Vol.256 (19), p.9830-9833
Hauptverfasser:	Salter, R S, Krinks, M H, Klee, C B, Neer, E J
Format:	Artikel
Sprache:	eng
Schlagworte:	adenylate cyclase Adenylyl Cyclases - metabolism Animals brain Calcium-Binding Proteins - pharmacology calmodulin Calmodulin - metabolism Calmodulin - pharmacology Calmodulin-Binding Proteins Cattle Cerebral Cortex - enzymology Enzyme Activation Guanylyl Imidodiphosphate - pharmacology Kinetics Nerve Tissue Proteins - pharmacology Phosphoprotein Phosphatases
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