Multidrug resistance proteins and topoisomerase IIalpha expression in colon cancer: association with metastatic potential

To investigate the role of multidrug resistance proteins and topoisomerase IIalpha in colon cancer. Tissue sections from 89 Dukes' stage B-D colon cancer patients were selected. The expression of multidrug resistance proteins and topoisomerase IIalpha in primary tumour cells was assessed by sta...

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Veröffentlicht in:	Pathology 2003-08, Vol.35 (4), p.315-318
Hauptverfasser:	Zorzos, Haralampos S, Lazaris, Andreas C, Korkolopoulou, Penelope A, Kavantzas, Nikolaos G, Tseleni-Balafouta, Sofia, Patsouris, Efstratios S, Tsavaris, Nikolaos V, Davaris, Panagiotis S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - secondary Adenoma - metabolism Adenoma - pathology Adult Aged Antigens, Neoplasm ATP Binding Cassette Transporter, Subfamily B - metabolism Biomarkers, Tumor Colonic Neoplasms - metabolism Colonic Neoplasms - pathology DNA Topoisomerases, Type II - metabolism DNA-Binding Proteins Drug Resistance, Multiple - physiology Female Humans Immunoenzyme Techniques Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis - physiopathology Male Middle Aged Multidrug Resistance-Associated Proteins - metabolism Neoplasm Invasiveness
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