Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200

CD200 (OX2) is a broadly distributed cell surface glycoprotein that interacts with a structurally related receptor (CD200R) expressed on rodent myeloid cells and is involved in regulation of macrophage function. We report the first characterization of human CD200R (hCD200R) and define its binding ch...

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Veröffentlicht in:	The Journal of immunology (1950) 2003-09, Vol.171 (6), p.3034-3046
Hauptverfasser:	Wright, Gavin J, Cherwinski, Holly, Foster-Cuevas, Mildred, Brooke, Gary, Puklavec, Michael J, Bigler, Mike, Song, Yaoli, Jenmalm, Maria, Gorman, Dan, McClanahan, Terri, Liu, Man-Ru, Brown, Marion H, Sedgwick, Jonathon D, Phillips, Joseph H, Barclay, A. Neil
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antibodies, Monoclonal - metabolism Antigens, CD Antigens, Surface - chemistry Antigens, Surface - genetics Antigens, Surface - metabolism Cells, Cultured Cloning, Molecular Humans Mice Mice, Inbred C57BL Molecular Sequence Data Multigene Family - immunology Orexin Receptors Organ Specificity - genetics Organ Specificity - immunology Protein Binding - genetics Protein Binding - immunology Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - metabolism Rats Receptors, Cell Surface Receptors, G-Protein-Coupled Receptors, Immunologic - chemistry Receptors, Immunologic - genetics Receptors, Immunologic - metabolism Receptors, Neuropeptide - chemistry Receptors, Neuropeptide - genetics Receptors, Neuropeptide - metabolism RNA, Messenger - analysis RNA, Messenger - metabolism Sequence Alignment Sequence Analysis, DNA Sequence Homology, Amino Acid Staining and Labeling
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