Use of erythropoietin for bloodless surgery in a Jehovah's witness infant
Summary We present a case of surgery in a 2‐month‐old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relat...
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description | Summary We present a case of surgery in a 2‐month‐old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relative emergency of surgery, a short erythropoietin course was instituted. Recombinant human erythropoietin (rHuEPO) at a dosage of 180 U·kg−1·day−1 was administered for 10 days preoperatively and for 4 days postoperatively. Iron was administered orally and intravenously over the entire perioperative period. No side‐effects from either erythropoietin or intravenously administered iron were observed. To our knowledge, this is the first case published of a short perioperative rHuEPO course in an infant. |
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I. ; Bourgeois, P. ; Goldman, L. J.</creator><creatorcontrib>Pérez‐Ferrer, A. ; De Vicente, J. ; Gredilla, E. ; García‐Vega, M. I. ; Bourgeois, P. ; Goldman, L. J.</creatorcontrib><description>Summary We present a case of surgery in a 2‐month‐old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relative emergency of surgery, a short erythropoietin course was instituted. Recombinant human erythropoietin (rHuEPO) at a dosage of 180 U·kg−1·day−1 was administered for 10 days preoperatively and for 4 days postoperatively. Iron was administered orally and intravenously over the entire perioperative period. No side‐effects from either erythropoietin or intravenously administered iron were observed. To our knowledge, this is the first case published of a short perioperative rHuEPO course in an infant.</description><identifier>ISSN: 1155-5645</identifier><identifier>EISSN: 1460-9592</identifier><identifier>DOI: 10.1046/j.1460-9592.2003.01012.x</identifier><identifier>PMID: 12950867</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Ltd</publisher><subject>Anemia - blood ; Anemia - drug therapy ; Anesthesia ; Anesthesia depending on patient's condition ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Loss, Surgical - prevention & control ; blood transfusion ; Blood Transfusion - psychology ; Emphysema - blood ; Emphysema - surgery ; erythropoietin ; Erythropoietin - administration & dosage ; Erythropoietin - therapeutic use ; Hematocrit ; Humans ; Infant ; iron ; Iron - blood ; Iron - therapeutic use ; Jehovah's Witnesses ; Jehovah's Witnesses - psychology ; Male ; Medical sciences ; Postoperative Care - methods ; Preoperative Care - methods ; Recombinant Proteins ; Religion and Medicine</subject><ispartof>Pediatric anesthesia, 2003-09, Vol.13 (7), p.633-636</ispartof><rights>2003 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3952-d578fb26b6c2d6c476d220a758d892fcd76ea4963d1d7930b7019a2da5479c333</citedby><cites>FETCH-LOGICAL-c3952-d578fb26b6c2d6c476d220a758d892fcd76ea4963d1d7930b7019a2da5479c333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1046%2Fj.1460-9592.2003.01012.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1046%2Fj.1460-9592.2003.01012.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15101360$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12950867$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pérez‐Ferrer, A.</creatorcontrib><creatorcontrib>De Vicente, J.</creatorcontrib><creatorcontrib>Gredilla, E.</creatorcontrib><creatorcontrib>García‐Vega, M. I.</creatorcontrib><creatorcontrib>Bourgeois, P.</creatorcontrib><creatorcontrib>Goldman, L. J.</creatorcontrib><title>Use of erythropoietin for bloodless surgery in a Jehovah's witness infant</title><title>Pediatric anesthesia</title><addtitle>Paediatr Anaesth</addtitle><description>Summary We present a case of surgery in a 2‐month‐old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relative emergency of surgery, a short erythropoietin course was instituted. Recombinant human erythropoietin (rHuEPO) at a dosage of 180 U·kg−1·day−1 was administered for 10 days preoperatively and for 4 days postoperatively. Iron was administered orally and intravenously over the entire perioperative period. No side‐effects from either erythropoietin or intravenously administered iron were observed. To our knowledge, this is the first case published of a short perioperative rHuEPO course in an infant.</description><subject>Anemia - blood</subject><subject>Anemia - drug therapy</subject><subject>Anesthesia</subject><subject>Anesthesia depending on patient's condition</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Loss, Surgical - prevention & control</subject><subject>blood transfusion</subject><subject>Blood Transfusion - psychology</subject><subject>Emphysema - blood</subject><subject>Emphysema - surgery</subject><subject>erythropoietin</subject><subject>Erythropoietin - administration & dosage</subject><subject>Erythropoietin - therapeutic use</subject><subject>Hematocrit</subject><subject>Humans</subject><subject>Infant</subject><subject>iron</subject><subject>Iron - blood</subject><subject>Iron - therapeutic use</subject><subject>Jehovah's Witnesses</subject><subject>Jehovah's Witnesses - psychology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Postoperative Care - methods</subject><subject>Preoperative Care - methods</subject><subject>Recombinant Proteins</subject><subject>Religion and Medicine</subject><issn>1155-5645</issn><issn>1460-9592</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkLtOwzAUhi0EouXyCsgLMCX4EtvxwIAqrkLAALPl2A5NlcbFTil9exxawcrkI_3f-X30AQAxyjEq-MUsxwVHmWSS5AQhmiOMMMm_dsD4N9hNM2YsY7xgI3AQ4wwhTAkn-2CEiWSo5GIM7t-ig76GLqz7afAL37i-6WDtA6xa723rYoRxGd4TAFOg4YOb-k89PY9w1fTdEDddrbv-COzVuo3uePsegreb69fJXfb4fHs_uXrMDJWMZJaJsq4Ir7ghlptCcEsI0oKVtpSkNlZwpwvJqcVWSIoqgbDUxGpWCGkopYfgbNO7CP5j6WKv5k00rm115_wyKkE5Tm0igeUGNMHHGFytFqGZ67BWGKlBo5qpwZYabKlBo_rRqL7S6sn2j2U1d_ZvcestAadbQEej2zrozjTxj2OpiHKUuMsNt2pat_73Aerl6mmY6DeLUI0S</recordid><startdate>200309</startdate><enddate>200309</enddate><creator>Pérez‐Ferrer, A.</creator><creator>De Vicente, J.</creator><creator>Gredilla, E.</creator><creator>García‐Vega, M. I.</creator><creator>Bourgeois, P.</creator><creator>Goldman, L. J.</creator><general>Blackwell Science Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200309</creationdate><title>Use of erythropoietin for bloodless surgery in a Jehovah's witness infant</title><author>Pérez‐Ferrer, A. ; De Vicente, J. ; Gredilla, E. ; García‐Vega, M. I. ; Bourgeois, P. ; Goldman, L. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3952-d578fb26b6c2d6c476d220a758d892fcd76ea4963d1d7930b7019a2da5479c333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Anemia - blood</topic><topic>Anemia - drug therapy</topic><topic>Anesthesia</topic><topic>Anesthesia depending on patient's condition</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Loss, Surgical - prevention & control</topic><topic>blood transfusion</topic><topic>Blood Transfusion - psychology</topic><topic>Emphysema - blood</topic><topic>Emphysema - surgery</topic><topic>erythropoietin</topic><topic>Erythropoietin - administration & dosage</topic><topic>Erythropoietin - therapeutic use</topic><topic>Hematocrit</topic><topic>Humans</topic><topic>Infant</topic><topic>iron</topic><topic>Iron - blood</topic><topic>Iron - therapeutic use</topic><topic>Jehovah's Witnesses</topic><topic>Jehovah's Witnesses - psychology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Postoperative Care - methods</topic><topic>Preoperative Care - methods</topic><topic>Recombinant Proteins</topic><topic>Religion and Medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pérez‐Ferrer, A.</creatorcontrib><creatorcontrib>De Vicente, J.</creatorcontrib><creatorcontrib>Gredilla, E.</creatorcontrib><creatorcontrib>García‐Vega, M. I.</creatorcontrib><creatorcontrib>Bourgeois, P.</creatorcontrib><creatorcontrib>Goldman, L. J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pérez‐Ferrer, A.</au><au>De Vicente, J.</au><au>Gredilla, E.</au><au>García‐Vega, M. I.</au><au>Bourgeois, P.</au><au>Goldman, L. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of erythropoietin for bloodless surgery in a Jehovah's witness infant</atitle><jtitle>Pediatric anesthesia</jtitle><addtitle>Paediatr Anaesth</addtitle><date>2003-09</date><risdate>2003</risdate><volume>13</volume><issue>7</issue><spage>633</spage><epage>636</epage><pages>633-636</pages><issn>1155-5645</issn><eissn>1460-9592</eissn><abstract>Summary We present a case of surgery in a 2‐month‐old infant of the Jehovah's Witness (JW) faith weighing 2.8 kg scheduled for left upper lobectomy because of congenital lobar emphysema. He presented with physiological anaemia (haematocrit 33.8%) in accordance with his age. Because of the relative emergency of surgery, a short erythropoietin course was instituted. Recombinant human erythropoietin (rHuEPO) at a dosage of 180 U·kg−1·day−1 was administered for 10 days preoperatively and for 4 days postoperatively. Iron was administered orally and intravenously over the entire perioperative period. No side‐effects from either erythropoietin or intravenously administered iron were observed. To our knowledge, this is the first case published of a short perioperative rHuEPO course in an infant.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>12950867</pmid><doi>10.1046/j.1460-9592.2003.01012.x</doi><tpages>4</tpages></addata></record> |
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subjects | Anemia - blood Anemia - drug therapy Anesthesia Anesthesia depending on patient's condition Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Loss, Surgical - prevention & control blood transfusion Blood Transfusion - psychology Emphysema - blood Emphysema - surgery erythropoietin Erythropoietin - administration & dosage Erythropoietin - therapeutic use Hematocrit Humans Infant iron Iron - blood Iron - therapeutic use Jehovah's Witnesses Jehovah's Witnesses - psychology Male Medical sciences Postoperative Care - methods Preoperative Care - methods Recombinant Proteins Religion and Medicine |
title | Use of erythropoietin for bloodless surgery in a Jehovah's witness infant |
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