Latent portasystemic encephalopathy. I. Nature of cerebral functional defects and their effect on fitness to drive

Forty patients with chronic liver disease and portal hypertension but without clinical signs of portasystemic encephalopathy (15 patients with nonalcoholic cirrhosis, 15 patients with alcoholic cirrhosis, and 10 patients with minimal EEG changes) and a control group of 12 patients with chronic alcoh...

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Veröffentlicht in:Digestive diseases and sciences 1981-07, Vol.26 (7), p.622-630
Hauptverfasser: Schomerus, H, Hamster, W, Blunck, H, Reinhard, U, Mayer, K, Dölle, W
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container_issue 7
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container_title Digestive diseases and sciences
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creator Schomerus, H
Hamster, W
Blunck, H
Reinhard, U
Mayer, K
Dölle, W
description Forty patients with chronic liver disease and portal hypertension but without clinical signs of portasystemic encephalopathy (15 patients with nonalcoholic cirrhosis, 15 patients with alcoholic cirrhosis, and 10 patients with minimal EEG changes) and a control group of 12 patients with chronic alcohol pancreatitis were studied using an extensive psychometric program, which, in the same form, is used for expert reports on driving capacity. Of the cirrhotic patients, 60% were considered unfit to drive; in 25% driving capacity was questionable, 15% (only nonalcoholic cirrhotics) were considered fit to drive. In contrast 75% of the patients with alcoholic pancreatitis were considered fit to drive. Major defects were found only in three heavy alcoholics. Patients with alcoholic cirrhosis scored lower than patients with nonalcoholic cirrhosis. This was due to differences in liver function rather than to the effect of alcohol consumption. Patients with minimal EEG changes were practically all considered unfit to drive.
doi_str_mv 10.1007/BF01367675
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subjects Adult
Automobile Driving
Brain Diseases - etiology
Brain Diseases - psychology
Chronic Disease
Humans
Hypertension, Portal - complications
Intelligence
Liver Diseases - complications
Memory, Short-Term
Middle Aged
Motor Activity
Personality
Psychometrics
title Latent portasystemic encephalopathy. I. Nature of cerebral functional defects and their effect on fitness to drive
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