Platelet-derived growth factor and its receptors are related to the progression of human muscular dystrophy: an immunohistochemical study

This study has examined the immunological localization of platelet‐derived growth factor (PDGF)‐A, PDGF‐B, and PDGF receptor (PDGFR) alpha and beta to clarify their role in the progression of muscular dystrophy. Biopsied frozen muscles from patients with Duchenne muscular dystrophy (DMD), Becker mus...

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Veröffentlicht in:	The Journal of pathology 2003-09, Vol.201 (1), p.149-159
Hauptverfasser:	Zhao, Yajuan, Haginoya, Kazuhiro, Sun, Guilian, Dai, Hongmei, Onuma, Akira, Iinuma, Kazuie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Biological and medical sciences Child Child, Preschool Disease Progression Diseases of striated muscles. Neuromuscular diseases dy mice Female fibrosis Humans Immunoenzyme Techniques Infant Male mdx mice Medical sciences Mice Mice, Inbred mdx Mice, Inbred Strains Muscle, Skeletal - metabolism Muscular Dystrophies - metabolism muscular dystrophy Muscular Dystrophy, Animal - metabolism Muscular Dystrophy, Duchenne - metabolism Neurology platelet-derived growth factor Platelet-Derived Growth Factor - metabolism platelet-derived growth factor receptor alpha platelet-derived growth factor receptor beta Proto-Oncogene Proteins c-sis - metabolism Receptor, Platelet-Derived Growth Factor alpha - metabolism Receptor, Platelet-Derived Growth Factor beta - metabolism Receptors, Platelet-Derived Growth Factor - metabolism
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