SOX2 Functions to Maintain Neural Progenitor Identity

Neural progenitors of the vertebrate CNS are defined by generic cellular characteristics, including their pseudoepithelial morphology and their ability to divide and differentiate. SOXB1 transcription factors, including the three closely related genes Sox1, Sox2, and Sox3, universally mark neural pr...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2003-08, Vol.39 (5), p.749-765
Hauptverfasser:	Graham, Victoria, Khudyakov, Jane, Ellis, Pamela, Pevny, Larysa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell cycle Cell Cycle - physiology Cell Differentiation - physiology Central Nervous System - cytology Central Nervous System - embryology Chick Embryo DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drosophila Gene Expression Regulation, Developmental HMGB Proteins Immunohistochemistry Insects Mice Neurons - physiology Nuclear Proteins - genetics Nuclear Proteins - metabolism Phenotype Rodents Signal Transduction - physiology SOXB1 Transcription Factors Stem cells Stem Cells - physiology Studies Transcription Factors
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