Mechanism of metronidazole-resistance by isolates of nitroreductase-producing Enterococcus gallinarum and Enterococcus casseliflavus from the human intestinal tract

Enterococcus casseliflavus and Enterococcus gallinarum strains resistant to metronidazole, nitrofurantoin and nitrofurazone were isolated from fecal samples of a patient with recurrent ulcerative colitis treated with metronidazole. Unlike other metronidazole-resistant bacteria, these strains produce...

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Veröffentlicht in:	FEMS microbiology letters 2003-08, Vol.225 (2), p.195-200
Hauptverfasser:	Rafii, Fatemeh, Wynne, Rebecca, Heinze, Thomas M., Paine, Donald D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Biological and medical sciences Chromatography, High Pressure Liquid Clostridium perfringens - growth & development Drug Resistance, Bacterial Enterococcus Enterococcus - drug effects Enterococcus - growth & development Enterococcus - isolation & purification Enterococcus - metabolism Feces - microbiology Fundamental and applied biological sciences. Psychology Humans Intestinal bacteria Intestines - microbiology Metronidazole Metronidazole - metabolism Metronidazole - pharmacology Microbiology Nitroreductase Nitroreductases - biosynthesis Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Spectrometry, Mass, Electrospray Ionization
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