Point mutation is responsible for Arabidopsis tz-201 mutant phenotype affecting thiamin biosynthesis

A point mutation in the thi1 gene, involved in the synthesis of thiamin, has been identified in a tz-201 mutant line of Arabidopsis thaliana. The mutation occurs in a conserved protein domain and prevents the mutant plants from synthesizing thiamin. Complementation assays in yeast thi4 mutant confir...

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