Trophoblastic Pulmonary Embolism
Trophoblastic embolism is subclinical in normal pregnancy, pronounced in eclampsia, and massive in hydatidiform mole. Self-limited acute respiratory distress arises in 3% to 10% of molar pregnancies at the time of uterine evacuation. Infrequently death occurs; the principal findings are trophoblasti...
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Veröffentlicht in: | Southern medical journal (Birmingham, Ala.) Ala.), 1981-08, Vol.74 (8), p.916-919 |
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container_title | Southern medical journal (Birmingham, Ala.) |
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creator | SMITH, J CHANDLER ALSULEIMAN, SULEIMAN A BISHOP, HENRY KASSAR, NAIM S JONAS, HARRY S |
description | Trophoblastic embolism is subclinical in normal pregnancy, pronounced in eclampsia, and massive in hydatidiform mole. Self-limited acute respiratory distress arises in 3% to 10% of molar pregnancies at the time of uterine evacuation. Infrequently death occurs; the principal findings are trophoblastic emboli in the pulmonary arterioles, edema of the lungs, and dilatation of the right side of the heart. Hyperthroidism may develop, and fibrin may line the alveolar walls. Pathogenetic mechanisms include heart failure, hyperthyroidism, dilutional anemia, and pulmonary arteriolar blockage. Infusions of fluid and whole blood tend to cause pulmonary overload, which may precipitate right-sided heart failure. Preferred therapy consists of diuresis and ventilatory support, especially with oxygen under positive end-expiratory pressure. |
doi_str_mv | 10.1097/00007611-198108000-00006 |
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Self-limited acute respiratory distress arises in 3% to 10% of molar pregnancies at the time of uterine evacuation. Infrequently death occurs; the principal findings are trophoblastic emboli in the pulmonary arterioles, edema of the lungs, and dilatation of the right side of the heart. Hyperthroidism may develop, and fibrin may line the alveolar walls. Pathogenetic mechanisms include heart failure, hyperthyroidism, dilutional anemia, and pulmonary arteriolar blockage. Infusions of fluid and whole blood tend to cause pulmonary overload, which may precipitate right-sided heart failure. Preferred therapy consists of diuresis and ventilatory support, especially with oxygen under positive end-expiratory pressure.</description><identifier>ISSN: 0038-4348</identifier><identifier>EISSN: 1541-8243</identifier><identifier>DOI: 10.1097/00007611-198108000-00006</identifier><identifier>PMID: 6267719</identifier><language>eng</language><publisher>United States: by the Southern Medical Association</publisher><subject>Adult ; Diuresis ; Female ; Humans ; Intermittent Positive-Pressure Ventilation ; Pregnancy ; Pulmonary Embolism - etiology ; Pulmonary Embolism - therapy ; Trophoblastic Neoplasms - complications ; Trophoblastic Neoplasms - therapy ; Uterine Neoplasms - complications ; Uterine Neoplasms - therapy</subject><ispartof>Southern medical journal (Birmingham, Ala.), 1981-08, Vol.74 (8), p.916-919</ispartof><rights>1981 by the Southern Medical Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3556-bf3189b0d9ba7f2234137221484dac1bf4c62bcc99b615242daf413d240d5b713</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27913,27914</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6267719$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SMITH, J CHANDLER</creatorcontrib><creatorcontrib>ALSULEIMAN, SULEIMAN A</creatorcontrib><creatorcontrib>BISHOP, HENRY</creatorcontrib><creatorcontrib>KASSAR, NAIM S</creatorcontrib><creatorcontrib>JONAS, HARRY S</creatorcontrib><title>Trophoblastic Pulmonary Embolism</title><title>Southern medical journal (Birmingham, Ala.)</title><addtitle>South Med J</addtitle><description>Trophoblastic embolism is subclinical in normal pregnancy, pronounced in eclampsia, and massive in hydatidiform mole. Self-limited acute respiratory distress arises in 3% to 10% of molar pregnancies at the time of uterine evacuation. Infrequently death occurs; the principal findings are trophoblastic emboli in the pulmonary arterioles, edema of the lungs, and dilatation of the right side of the heart. Hyperthroidism may develop, and fibrin may line the alveolar walls. Pathogenetic mechanisms include heart failure, hyperthyroidism, dilutional anemia, and pulmonary arteriolar blockage. Infusions of fluid and whole blood tend to cause pulmonary overload, which may precipitate right-sided heart failure. Preferred therapy consists of diuresis and ventilatory support, especially with oxygen under positive end-expiratory pressure.</description><subject>Adult</subject><subject>Diuresis</subject><subject>Female</subject><subject>Humans</subject><subject>Intermittent Positive-Pressure Ventilation</subject><subject>Pregnancy</subject><subject>Pulmonary Embolism - etiology</subject><subject>Pulmonary Embolism - therapy</subject><subject>Trophoblastic Neoplasms - complications</subject><subject>Trophoblastic Neoplasms - therapy</subject><subject>Uterine Neoplasms - complications</subject><subject>Uterine Neoplasms - therapy</subject><issn>0038-4348</issn><issn>1541-8243</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1PwzAMhiMEGmPwE5B64laIkzQfRzSNDwkJDuMcJWmqFdJlJK0m_j0dG7vhi2X7fW3rQagAfAtYiTs8huAAJSgJWI5VuWvxEzSFikEpCaOnaIoxlSWjTJ6ji5w_dqZK8gmacMKFADVFxTLFzSraYHLfuuJtCF1cm_RdLDobQ5u7S3TWmJD91SHP0PvDYjl_Kl9eH5_n9y-lo1XFS9tQkMriWlkjGkIoAyoIASZZbRzYhjlOrHNKWQ4VYaQ2zSipCcN1ZQXQGbrZ792k-DX43Ouuzc6HYNY-DlkLygEzJkeh3Atdijkn3-hNarvxZQ1Y7-DoPzj6COe3xUfr9eHGYDtfH40HGuOc7efbGHqf8mcYtj7plTehX-n_mNMfAa1s_g</recordid><startdate>198108</startdate><enddate>198108</enddate><creator>SMITH, J CHANDLER</creator><creator>ALSULEIMAN, SULEIMAN A</creator><creator>BISHOP, HENRY</creator><creator>KASSAR, NAIM S</creator><creator>JONAS, HARRY S</creator><general>by the Southern Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198108</creationdate><title>Trophoblastic Pulmonary Embolism</title><author>SMITH, J CHANDLER ; ALSULEIMAN, SULEIMAN A ; BISHOP, HENRY ; KASSAR, NAIM S ; JONAS, HARRY S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3556-bf3189b0d9ba7f2234137221484dac1bf4c62bcc99b615242daf413d240d5b713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adult</topic><topic>Diuresis</topic><topic>Female</topic><topic>Humans</topic><topic>Intermittent Positive-Pressure Ventilation</topic><topic>Pregnancy</topic><topic>Pulmonary Embolism - etiology</topic><topic>Pulmonary Embolism - therapy</topic><topic>Trophoblastic Neoplasms - complications</topic><topic>Trophoblastic Neoplasms - therapy</topic><topic>Uterine Neoplasms - complications</topic><topic>Uterine Neoplasms - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SMITH, J CHANDLER</creatorcontrib><creatorcontrib>ALSULEIMAN, SULEIMAN A</creatorcontrib><creatorcontrib>BISHOP, HENRY</creatorcontrib><creatorcontrib>KASSAR, NAIM S</creatorcontrib><creatorcontrib>JONAS, HARRY S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SMITH, J CHANDLER</au><au>ALSULEIMAN, SULEIMAN A</au><au>BISHOP, HENRY</au><au>KASSAR, NAIM S</au><au>JONAS, HARRY S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trophoblastic Pulmonary Embolism</atitle><jtitle>Southern medical journal (Birmingham, Ala.)</jtitle><addtitle>South Med J</addtitle><date>1981-08</date><risdate>1981</risdate><volume>74</volume><issue>8</issue><spage>916</spage><epage>919</epage><pages>916-919</pages><issn>0038-4348</issn><eissn>1541-8243</eissn><abstract>Trophoblastic embolism is subclinical in normal pregnancy, pronounced in eclampsia, and massive in hydatidiform mole. Self-limited acute respiratory distress arises in 3% to 10% of molar pregnancies at the time of uterine evacuation. Infrequently death occurs; the principal findings are trophoblastic emboli in the pulmonary arterioles, edema of the lungs, and dilatation of the right side of the heart. Hyperthroidism may develop, and fibrin may line the alveolar walls. Pathogenetic mechanisms include heart failure, hyperthyroidism, dilutional anemia, and pulmonary arteriolar blockage. Infusions of fluid and whole blood tend to cause pulmonary overload, which may precipitate right-sided heart failure. Preferred therapy consists of diuresis and ventilatory support, especially with oxygen under positive end-expiratory pressure.</abstract><cop>United States</cop><pub>by the Southern Medical Association</pub><pmid>6267719</pmid><doi>10.1097/00007611-198108000-00006</doi><tpages>4</tpages></addata></record> |
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subjects | Adult Diuresis Female Humans Intermittent Positive-Pressure Ventilation Pregnancy Pulmonary Embolism - etiology Pulmonary Embolism - therapy Trophoblastic Neoplasms - complications Trophoblastic Neoplasms - therapy Uterine Neoplasms - complications Uterine Neoplasms - therapy |
title | Trophoblastic Pulmonary Embolism |
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