Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses
Purpose: To examine long-term survival after angioplasty and stenting of atherosclerotic renal artery stenosis (RAS). Methods: Over a 5-year period, 241 consecutive patients (153 men; mean age 67±9 years, range 44–84) were treated with angioplasty and stent implantation for 355 ostial renal stenoses...
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| Veröffentlicht in: | Journal of endovascular therapy 2003-06, Vol.10 (3), p.539-545 |
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| container_title | Journal of endovascular therapy |
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| creator | Zeller, Thomas Müller, Christian Frank, Ulrich Bürgelin, Karlheinz Schwarzwälder, Uwe Horn, Barbara Roskamm, Helmut Neumann, Franz-Josef |
| description | Purpose:
To examine long-term survival after angioplasty and stenting of atherosclerotic renal artery stenosis (RAS).
Methods:
Over a 5-year period, 241 consecutive patients (153 men; mean age 67±9 years, range 44–84) were treated with angioplasty and stent implantation for 355 ostial renal stenoses >70%. The procedures were performed in standard fashion using a variety of stents. For survival analysis, the patients were divided into 3 groups based on baseline creatinine levels: group 1: 115 (48%) patients with normal renal function (creatinine 2.5 mg/dL).
Results:
All patients were treated successfully without any procedure-related mortality. The 30-day mortality was 0.4% (1/241). Twenty-two patients died during a follow-up of 27±15 months (range 1–60) (overall survival 91%). The causes of death were cardiac (congestive heart failure or myocardial infarction, 73%), stroke (13.5%), and malignant disease (13.5%). The survival rate was significantly lower (29.6%) in patients with a baseline serum creatinine >2.5 mg/dL (p |
| doi_str_mv | 10.1177/152660280301000320 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73608302</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_152660280301000320</sage_id><sourcerecordid>73608302</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2520-5f3e1fa67ea74eb1c17937b9a07a25cddf44bdbe73e5612765105ca9e37baf243</originalsourceid><addsrcrecordid>eNp9kE1Lw0AQhhdRrFb_gAfJyVvszG52tzmW4hcUC1bPYbOZ1JQ0qbtJof_erS14ELzMzOF5X5iHsRuEe0StRyi5UsDHIAABQHA4YRcoExmjlHC6v7mK98SAXXq_AuDIEc_ZAHkqOCp1wV4XvdtWW1NHpuzIRYuOmq5qllFbRgvakqNo0n2Sa72tw-wqG819VwX-jZowJy6kdj-x1pO_YmelqT1dH_eQfTw-vE-f49n86WU6mcWWSw6xLAVhaZQmoxPK0aJOhc5TA9pwaYuiTJK8yEkLkgq5VhJBWpNSgEzJEzFkd4fejWu_evJdtq68pbo2DbW9z7RQMBbAA8gPoA0veEdltnHV2rhdhpDtLWZ_LYbQ7bG9z9dU_EaO2gIwOgDeLClbtb0LLvx_ld-KA3oB</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73608302</pqid></control><display><type>article</type><title>Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses</title><source>MEDLINE</source><source>SAGE Complete</source><creator>Zeller, Thomas ; Müller, Christian ; Frank, Ulrich ; Bürgelin, Karlheinz ; Schwarzwälder, Uwe ; Horn, Barbara ; Roskamm, Helmut ; Neumann, Franz-Josef</creator><creatorcontrib>Zeller, Thomas ; Müller, Christian ; Frank, Ulrich ; Bürgelin, Karlheinz ; Schwarzwälder, Uwe ; Horn, Barbara ; Roskamm, Helmut ; Neumann, Franz-Josef</creatorcontrib><description>Purpose:
To examine long-term survival after angioplasty and stenting of atherosclerotic renal artery stenosis (RAS).
Methods:
Over a 5-year period, 241 consecutive patients (153 men; mean age 67±9 years, range 44–84) were treated with angioplasty and stent implantation for 355 ostial renal stenoses >70%. The procedures were performed in standard fashion using a variety of stents. For survival analysis, the patients were divided into 3 groups based on baseline creatinine levels: group 1: 115 (48%) patients with normal renal function (creatinine <1.2 mg/dL); group 2: 93 (39%) patients with moderately impaired renal function (creatinine 1.2 to 2.5 mg/dL); and group 3: 33 (13%) patients with severely impaired renal function (creatinine >2.5 mg/dL).
Results:
All patients were treated successfully without any procedure-related mortality. The 30-day mortality was 0.4% (1/241). Twenty-two patients died during a follow-up of 27±15 months (range 1–60) (overall survival 91%). The causes of death were cardiac (congestive heart failure or myocardial infarction, 73%), stroke (13.5%), and malignant disease (13.5%). The survival rate was significantly lower (29.6%) in patients with a baseline serum creatinine >2.5 mg/dL (p<0.0001) than in groups 2 (89.1%) or 1 (95.4%). Long-term survival without hemodialysis or restenosis was 66.6% at 48 months. Independent predictors for a reduced survival were left ventricle function (HR 2.59, 95% CI 1.45 to 4.63, p=0.001 for each 15% incremental decrease), age (HR 1.13, 95% CI 1.03 to 1.25, p=0.011), and baseline renal function (HR 1.58, 95% CI 1.10 to 2.29, p=0.014).
Conclusions:
Survival after successful stenting for severe ostial RAS depends on baseline serum creatinine and left ventricle function. Efforts must be made to avoid the development of advanced ischemic nephropathy and congestive heart failure.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1177/152660280301000320</identifier><identifier>PMID: 12932166</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arteriosclerosis - complications ; Arteriosclerosis - mortality ; Arteriosclerosis - surgery ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications - epidemiology ; Prospective Studies ; Renal Artery Obstruction - complications ; Renal Artery Obstruction - mortality ; Renal Artery Obstruction - surgery ; Severity of Illness Index ; Stents - adverse effects ; Survival Rate</subject><ispartof>Journal of endovascular therapy, 2003-06, Vol.10 (3), p.539-545</ispartof><rights>2003 SAGE Publications</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2520-5f3e1fa67ea74eb1c17937b9a07a25cddf44bdbe73e5612765105ca9e37baf243</citedby><cites>FETCH-LOGICAL-c2520-5f3e1fa67ea74eb1c17937b9a07a25cddf44bdbe73e5612765105ca9e37baf243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/152660280301000320$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/152660280301000320$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12932166$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zeller, Thomas</creatorcontrib><creatorcontrib>Müller, Christian</creatorcontrib><creatorcontrib>Frank, Ulrich</creatorcontrib><creatorcontrib>Bürgelin, Karlheinz</creatorcontrib><creatorcontrib>Schwarzwälder, Uwe</creatorcontrib><creatorcontrib>Horn, Barbara</creatorcontrib><creatorcontrib>Roskamm, Helmut</creatorcontrib><creatorcontrib>Neumann, Franz-Josef</creatorcontrib><title>Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>Purpose:
To examine long-term survival after angioplasty and stenting of atherosclerotic renal artery stenosis (RAS).
Methods:
Over a 5-year period, 241 consecutive patients (153 men; mean age 67±9 years, range 44–84) were treated with angioplasty and stent implantation for 355 ostial renal stenoses >70%. The procedures were performed in standard fashion using a variety of stents. For survival analysis, the patients were divided into 3 groups based on baseline creatinine levels: group 1: 115 (48%) patients with normal renal function (creatinine <1.2 mg/dL); group 2: 93 (39%) patients with moderately impaired renal function (creatinine 1.2 to 2.5 mg/dL); and group 3: 33 (13%) patients with severely impaired renal function (creatinine >2.5 mg/dL).
Results:
All patients were treated successfully without any procedure-related mortality. The 30-day mortality was 0.4% (1/241). Twenty-two patients died during a follow-up of 27±15 months (range 1–60) (overall survival 91%). The causes of death were cardiac (congestive heart failure or myocardial infarction, 73%), stroke (13.5%), and malignant disease (13.5%). The survival rate was significantly lower (29.6%) in patients with a baseline serum creatinine >2.5 mg/dL (p<0.0001) than in groups 2 (89.1%) or 1 (95.4%). Long-term survival without hemodialysis or restenosis was 66.6% at 48 months. Independent predictors for a reduced survival were left ventricle function (HR 2.59, 95% CI 1.45 to 4.63, p=0.001 for each 15% incremental decrease), age (HR 1.13, 95% CI 1.03 to 1.25, p=0.011), and baseline renal function (HR 1.58, 95% CI 1.10 to 2.29, p=0.014).
Conclusions:
Survival after successful stenting for severe ostial RAS depends on baseline serum creatinine and left ventricle function. Efforts must be made to avoid the development of advanced ischemic nephropathy and congestive heart failure.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arteriosclerosis - complications</subject><subject>Arteriosclerosis - mortality</subject><subject>Arteriosclerosis - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - epidemiology</subject><subject>Prospective Studies</subject><subject>Renal Artery Obstruction - complications</subject><subject>Renal Artery Obstruction - mortality</subject><subject>Renal Artery Obstruction - surgery</subject><subject>Severity of Illness Index</subject><subject>Stents - adverse effects</subject><subject>Survival Rate</subject><issn>1526-6028</issn><issn>1545-1550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRrFb_gAfJyVvszG52tzmW4hcUC1bPYbOZ1JQ0qbtJof_erS14ELzMzOF5X5iHsRuEe0StRyi5UsDHIAABQHA4YRcoExmjlHC6v7mK98SAXXq_AuDIEc_ZAHkqOCp1wV4XvdtWW1NHpuzIRYuOmq5qllFbRgvakqNo0n2Sa72tw-wqG819VwX-jZowJy6kdj-x1pO_YmelqT1dH_eQfTw-vE-f49n86WU6mcWWSw6xLAVhaZQmoxPK0aJOhc5TA9pwaYuiTJK8yEkLkgq5VhJBWpNSgEzJEzFkd4fejWu_evJdtq68pbo2DbW9z7RQMBbAA8gPoA0veEdltnHV2rhdhpDtLWZ_LYbQ7bG9z9dU_EaO2gIwOgDeLClbtb0LLvx_ld-KA3oB</recordid><startdate>200306</startdate><enddate>200306</enddate><creator>Zeller, Thomas</creator><creator>Müller, Christian</creator><creator>Frank, Ulrich</creator><creator>Bürgelin, Karlheinz</creator><creator>Schwarzwälder, Uwe</creator><creator>Horn, Barbara</creator><creator>Roskamm, Helmut</creator><creator>Neumann, Franz-Josef</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200306</creationdate><title>Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses</title><author>Zeller, Thomas ; Müller, Christian ; Frank, Ulrich ; Bürgelin, Karlheinz ; Schwarzwälder, Uwe ; Horn, Barbara ; Roskamm, Helmut ; Neumann, Franz-Josef</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2520-5f3e1fa67ea74eb1c17937b9a07a25cddf44bdbe73e5612765105ca9e37baf243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arteriosclerosis - complications</topic><topic>Arteriosclerosis - mortality</topic><topic>Arteriosclerosis - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - epidemiology</topic><topic>Prospective Studies</topic><topic>Renal Artery Obstruction - complications</topic><topic>Renal Artery Obstruction - mortality</topic><topic>Renal Artery Obstruction - surgery</topic><topic>Severity of Illness Index</topic><topic>Stents - adverse effects</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zeller, Thomas</creatorcontrib><creatorcontrib>Müller, Christian</creatorcontrib><creatorcontrib>Frank, Ulrich</creatorcontrib><creatorcontrib>Bürgelin, Karlheinz</creatorcontrib><creatorcontrib>Schwarzwälder, Uwe</creatorcontrib><creatorcontrib>Horn, Barbara</creatorcontrib><creatorcontrib>Roskamm, Helmut</creatorcontrib><creatorcontrib>Neumann, Franz-Josef</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of endovascular therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zeller, Thomas</au><au>Müller, Christian</au><au>Frank, Ulrich</au><au>Bürgelin, Karlheinz</au><au>Schwarzwälder, Uwe</au><au>Horn, Barbara</au><au>Roskamm, Helmut</au><au>Neumann, Franz-Josef</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses</atitle><jtitle>Journal of endovascular therapy</jtitle><addtitle>J Endovasc Ther</addtitle><date>2003-06</date><risdate>2003</risdate><volume>10</volume><issue>3</issue><spage>539</spage><epage>545</epage><pages>539-545</pages><issn>1526-6028</issn><eissn>1545-1550</eissn><abstract>Purpose:
To examine long-term survival after angioplasty and stenting of atherosclerotic renal artery stenosis (RAS).
Methods:
Over a 5-year period, 241 consecutive patients (153 men; mean age 67±9 years, range 44–84) were treated with angioplasty and stent implantation for 355 ostial renal stenoses >70%. The procedures were performed in standard fashion using a variety of stents. For survival analysis, the patients were divided into 3 groups based on baseline creatinine levels: group 1: 115 (48%) patients with normal renal function (creatinine <1.2 mg/dL); group 2: 93 (39%) patients with moderately impaired renal function (creatinine 1.2 to 2.5 mg/dL); and group 3: 33 (13%) patients with severely impaired renal function (creatinine >2.5 mg/dL).
Results:
All patients were treated successfully without any procedure-related mortality. The 30-day mortality was 0.4% (1/241). Twenty-two patients died during a follow-up of 27±15 months (range 1–60) (overall survival 91%). The causes of death were cardiac (congestive heart failure or myocardial infarction, 73%), stroke (13.5%), and malignant disease (13.5%). The survival rate was significantly lower (29.6%) in patients with a baseline serum creatinine >2.5 mg/dL (p<0.0001) than in groups 2 (89.1%) or 1 (95.4%). Long-term survival without hemodialysis or restenosis was 66.6% at 48 months. Independent predictors for a reduced survival were left ventricle function (HR 2.59, 95% CI 1.45 to 4.63, p=0.001 for each 15% incremental decrease), age (HR 1.13, 95% CI 1.03 to 1.25, p=0.011), and baseline renal function (HR 1.58, 95% CI 1.10 to 2.29, p=0.014).
Conclusions:
Survival after successful stenting for severe ostial RAS depends on baseline serum creatinine and left ventricle function. Efforts must be made to avoid the development of advanced ischemic nephropathy and congestive heart failure.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>12932166</pmid><doi>10.1177/152660280301000320</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of endovascular therapy, 2003-06, Vol.10 (3), p.539-545 |
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| subjects | Adult Aged Aged, 80 and over Arteriosclerosis - complications Arteriosclerosis - mortality Arteriosclerosis - surgery Female Humans Male Middle Aged Postoperative Complications - epidemiology Prospective Studies Renal Artery Obstruction - complications Renal Artery Obstruction - mortality Renal Artery Obstruction - surgery Severity of Illness Index Stents - adverse effects Survival Rate |
| title | Survival after Stenting of Severe Atherosclerotic Ostial Renal Artery Stenoses |
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