Enhancer timing of Hox gene expression: deletion of the endogenous Hoxc8 early enhancer

The proper expression of Hox genes is necessary for the accurate patterning of the body plan. The elucidation of the developmental genetic basis of transcriptional regulation of Hox genes by the study of their cis-regulatory elements provides crucial information regarding the establishment of axial...

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Veröffentlicht in:	Development (Cambridge) 2003-10, Vol.130 (20), p.4823-4834
Hauptverfasser:	Juan, Aster H, Ruddle, Frank H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Bone and Bones - embryology Bone and Bones - metabolism Enhancer Elements, Genetic Gene Expression Regulation, Developmental Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Mice Mice, Knockout Molecular Sequence Data Sequence Deletion
Online-Zugang:	Volltext
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