Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line

MUC1 is a polymorphic, highly glycosylated, type I transmembrane protein expressed by ductal epithelial cells of many organs including pancreas, breast, gastrointestinal tract, and airway. MUC1 is overexpressed and differentially glycosylated by adenocarcinomas that arise in these organs, and is bel...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2003-08, Vol.63 (16), p.5011-5020
Hauptverfasser:	KOHLGRAF, Karl G, GAWRON, Andrew J, HIGASHI, Michiyo, MEZA, Jane L, BURDICK, Michael D, KITAJIMA, Shinichi, KELLY, David L, CAFFREY, Thomas C, HOLLINGSWORTH, Michael A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - analysis Biological and medical sciences CD24 Antigen Cytoplasm - chemistry Dissemination Humans Lung Neoplasms - secondary Lymphatic Metastasis Medical sciences Membrane Glycoproteins Mice Mucin-1 - chemistry Mucin-1 - genetics Mucin-1 - physiology Neoplasm Invasiveness Pancreatic Neoplasms - pathology Peptide Fragments - chemistry Peptide Fragments - genetics Peptide Fragments - physiology Protein Isoforms Transfection Tumor cell Tumor Cells, Cultured Tumors
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