A linkage study of manic-depressive disorder with HLA antigens, blood groups, serum proteins and red cell enzymes

Families with a two-generational history of affective disorder and well and ill sibs were selected from a population of bipolar manic-depressive patients and typed for HLA antigens, blood groups, serum proteins and red cell enzymes. Segregation of specific HLA alleles was not associated with affecti...

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